Hospital de Santa Maria, Lisboa, Portugal.
Clin Transl Oncol. 2010 Aug;12(8):576-80. doi: 10.1007/s12094-010-0557-x.
Tracheal chondrosarcoma are rare diseases, with only 15 cases previously described in the literature between 1959 and 2008. Here we present a rare case of tracheal chondrosarcoma and a review of the literature. Our patient, a 72-year-old man, had progressive throat pain for 2 years before diagnosis. Clinical and imaging investigation revealed a giant tracheal mass that was partially debulked by laser for symptomatic relief. Histologically, the mass was characterized as a low-grade tracheal chondrosarcoma. The patient underwent external-beam radiotherapy (EBRT) and received 60 Gy. At the time this report was written, 7 years after the end of the treatment, the patient was alive and asymptomatic without evidence of locoregional disease. This case and some described in the literature demonstrate the value of EBRT as a single treatment modality in achieving local control. More experience is required to establish the definitive role of radiotherapy in low-grade tracheal chondrosarcoma.
气管软骨肉瘤是罕见的疾病，仅在 1959 年至 2008 年间的文献中描述过 15 例。在此，我们报告了一例罕见的气管软骨肉瘤病例，并对文献进行了回顾。我们的患者为 72 岁男性，在诊断前有 2 年的进行性咽喉痛病史。临床和影像学检查显示为巨大的气管肿块，采用激光部分减瘤以缓解症状。组织学上，该肿块为低度气管软骨肉瘤。患者接受了外照射放疗（EBRT）并接受了 60Gy 的照射。在本报告撰写时，即治疗结束 7 年后，患者仍存活且无症状，无局部疾病证据。该病例和一些文献中的病例表明，EBRT 作为单一治疗方式可实现局部控制。需要更多的经验来确定放疗在低度气管软骨肉瘤中的明确作用。
