Research Center for Minimally Invasive Surgery, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Center for Thoracic Surgery, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Acta Chir Belg. 2022 Oct;122(5):361-365. doi: 10.1080/00015458.2020.1863039. Epub 2020 Dec 25.
Tracheal chondrosarcoma is an extremely rare, slow-growing, malignant tumour. This study aims to analyze the cases of tracheal chondrosarcoma published in the literature and our case report, in order to better define tracheal chondrosarcoma management. A systematic review of the English literature was carried out for fully described tracheal chondrosarcoma cases. Additionally, we reported a new case of a 58-year-old man undergoing tracheal resection and reconstruction for tracheal chondrosarcoma. To date, 30 cases were published. This tumour predominantly involved male patients (93%; median age: 65 years), generally conditioning dyspnoea and cough. Most of the patients underwent tracheal resection with end-to-end anastomosis, without recurrence (median follow-up: 2 years). Tumours endoscopically treated recurred in half cases. Tracheal resection is the treatment of choice for chondrosarcoma, with an excellent prognosis. Endoscopic treatment and/or radiotherapy should be indicated for patients unfit for surgery.
气管软骨肉瘤是一种极为罕见、生长缓慢、恶性的肿瘤。本研究旨在分析文献中报道的气管软骨肉瘤病例和我们的病例报告，以便更好地定义气管软骨肉瘤的治疗方法。我们对英文文献进行了系统回顾，纳入了所有充分描述的气管软骨肉瘤病例。此外，我们报告了一例 58 岁男性患者因气管软骨肉瘤行气管切除和重建的新病例。迄今为止，共发表了 30 例病例。该肿瘤主要累及男性患者（93%；中位年龄：65 岁），通常表现为呼吸困难和咳嗽。大多数患者接受了气管端端吻合的切除术，无复发（中位随访时间：2 年）。内镜下治疗的肿瘤有一半复发。气管切除术是软骨肉瘤的治疗选择，预后良好。对于不适合手术的患者，应考虑内镜治疗和/或放疗。
