Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany.
Bioinformatics. 2010 Oct 1;26(19):2480-1. doi: 10.1093/bioinformatics/btq443. Epub 2010 Aug 12.
Protein microarrays are well-established as sensitive tools for proteomics. Particularly, the microspot immunoassay (MIA) platform enables a quantitative analysis of (phospho-) proteins in complex solutions (e.g. cell lysates or blood plasma) and with low consumption of samples and reagents. Despite numerous biological and clinical applications of MIAs there is currently no user-friendly open source data analysis software available with versatile options for data analysis and data visualization. Here, we introduce the open source software QuantProReloaded that is specifically designed for the analysis of data from MIA experiments.
QuantProReloaded is written in R and Java and is open for download under the BSB license at http://code.google.com/p/quantproreloaded/.
蛋白质微阵列已经成为蛋白质组学中敏感的工具。特别是，微孔免疫分析（MIA）平台能够定量分析复杂溶液中的（磷酸化）蛋白质（例如细胞裂解物或血浆），并且消耗的样品和试剂很少。尽管 MIA 具有许多生物学和临床应用，但目前尚无用户友好的开源数据分析软件，该软件具有灵活的数据分析和数据可视化选项。在这里，我们介绍专门为 MIA 实验数据分析而设计的开源软件 QuantProReloaded。
QuantProReloaded 是用 R 和 Java 编写的，并根据 BSB 许可证在 http://code.google.com/p/quantproreloaded/ 上提供下载。
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