Sandal Massimo, Benedetti Fabrizio, Brucale Marco, Gomez-Casado Alberto, Samorì Bruno
Department of Biochemistry, University of Bologna, Bologna, Italy.
Bioinformatics. 2009 Jun 1;25(11):1428-30. doi: 10.1093/bioinformatics/btp180. Epub 2009 Mar 31.
Hooke is an open source, extensible software intended for analysis of atomic force microscope (AFM)-based single molecule force spectroscopy (SMFS) data. We propose it as a platform on which published and new algorithms for SMFS analysis can be integrated in a standard, open fashion, as a general solution to the current lack of a standard software for SMFS data analysis. Specific features and support for file formats are coded as independent plugins. Any user can code new plugins, extending the software capabilities. Basic automated dataset filtering and semi-automatic analysis facilities are included.
Software and documentation are available at (http://code.google.com/p/hooke). Hooke is a free software under the GNU Lesser General Public License.
Hooke是一款开源、可扩展的软件，旨在分析基于原子力显微镜（AFM）的单分子力谱（SMFS）数据。我们将其作为一个平台来推荐，在这个平台上，已发表的和新的SMFS分析算法能够以标准、开放的方式进行整合，作为解决当前缺乏SMFS数据分析标准软件这一问题的通用方案。特定功能和对文件格式的支持被编码为独立的插件。任何用户都可以编写新的插件，扩展软件功能。软件包含基本的自动数据集过滤和半自动分析工具。
软件和文档可在（http://code.google.com/p/hooke）获取。Hooke是一款遵循GNU Lesser General Public License的免费软件。
