Waring J P, Sanowski R A, Sawyer R L, Woods C A, Foutch P G
Department of Internal Medicine, Carl I. Hayden Veterans Administration Medical Center, Phoenix, Arizona 85012.
Gastrointest Endosc. 1991 May-Jun;37(3):295-8. doi: 10.1016/s0016-5107(91)70718-9.
Several options are available to the gastroenterologist for the endoscopic control of peptic ulcer hemorrhage. Sixty men (mean age, 62 years) were stratified into those with actively bleeding ulcers or ulcers with stigmata of recent hemorrhage, and then randomized to treatment with injection sclerosis or the multipolar probe until bleeding ceased. There were no significant differences between the randomized groups in terms of age, ulcer size, or transfusion requirements. We achieved hemostasis in 95% of all patients. Re-bleeding rates were 25% and 23% in patients treated with the multipolar probe and injection sclerosis, respectively. There was no significant difference in mortality (14% multipolar probe, 7% injection sclerosis). Patients over the age of 70, those whose onset of bleeding was while an inpatient, and those with an ulcer larger than 2 cm were more likely to have a poor outcome, regardless of the type of endoscopic therapy. Injection sclerosis and multipolar electrocoagulation are equally effective in controlling bleeding from peptic ulcer.
胃肠病学家在内镜下控制消化性溃疡出血有多种选择。60名男性（平均年龄62岁）被分为活动性出血溃疡或有近期出血迹象的溃疡患者，然后随机接受注射硬化剂或多极探头治疗，直至出血停止。随机分组的两组在年龄、溃疡大小或输血需求方面无显著差异。我们在所有患者中实现了95%的止血率。接受多极探头和注射硬化剂治疗的患者再出血率分别为25%和23%。死亡率无显著差异（多极探头组为14%，注射硬化剂组为7%）。无论内镜治疗类型如何，70岁以上的患者、住院期间出血的患者以及溃疡大于2厘米的患者更有可能预后不良。注射硬化剂和多极电凝在控制消化性溃疡出血方面同样有效。
