[叠氮胸苷与神经系统]
[Azidothymidine and the nervous system].
作者信息
Riedel R R, Bader L, Gürtler L, Eberle J, Günther W, Naber D
机构信息
Univ.-Nerven-Klinik München.
出版信息
Fortschr Med. 1991 May 10;109(14):302-6.
PMID:2071083
Abstract
By December 1988 reports on 525 ARC- (AIDS-Related Complex) and AIDS-patients with neurological or neuropsychological signs treated with Zidovudine (AZT = 3'-Azido-2,3'Dideoxythymidine) had been published in literature. In 204 (38.8%) cases of HIV infection a temporary improvement in the neurological deficits was reported. Peripheral and central neurological side-effects were observed in 124 (23.6%) patients.
摘要
到1988年12月，关于525例接受齐多夫定（AZT = 3'-叠氮基-2,3'-双脱氧胸苷）治疗的伴有神经或神经心理症状的艾滋病相关综合征（ARC）和艾滋病患者的报告已发表在文献中。在204例（38.8%）HIV感染病例中，报告称神经功能缺损有暂时改善。124例（23.6%）患者出现了外周和中枢神经系统副作用。
Zotero 插件