Oksenhendler E
Département d'Immunopathologie et d'Hématologie, Hôpital Saint Louis, Paris, France.
Nouv Rev Fr Hematol (1978). 1989;31(2):69-72.
Azidothymidine is active against HIV and effective in patients with AIDS or ARC, as it clearly prolongs life. However the rapid development and marketing of this drug has left some crucial questions under discussion. Trials all over the world are currently under way to confirm the effectiveness and toxicity of AZT when administered for a prolonged period, to appreciate its potential benefits in patients in other HIV-related conditions and to determine whether it can prevent evolution towards ARC or AIDS in HIV asymptomatic carriers.
叠氮胸苷对艾滋病病毒有活性，对患有艾滋病或艾滋病相关综合征的患者有效，因为它能显著延长生命。然而，这种药物的迅速研发和上市留下了一些关键问题有待探讨。目前世界各地都在进行试验，以确认长期服用叠氮胸苷的有效性和毒性，评估其在其他与艾滋病病毒相关病症患者中的潜在益处，并确定它是否能预防艾滋病病毒无症状携带者发展为艾滋病相关综合征或艾滋病。
