Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-Dong, Kangnam-Ku, Seoul, 135-710, South Korea.
Neuroradiology. 2010 Dec;52(12):1179-84. doi: 10.1007/s00234-010-0758-6. Epub 2010 Aug 18.
Metaplastic ossification is a rare event in nasal polyps. The purpose of this study was to review the computed tomography (CT) and magnetic resonance (MR) imaging findings of nasal polyps with metaplastic ossification.
CT (n=5) and MR (n=3) images of five patients (four men and one woman; mean age, 59 years) with surgically proven nasal polyp with metaplastic ossification were retrospectively reviewed. The location and morphologic characteristics of metaplastic ossification were documented as well.
All lesions were seen as lobulated (n=3), ovoid (n=1), or dumbbell-shaped (n=1) benign-looking masses with a mean size of 3.7 cm (range, 2.4-6.5 cm), located unilaterally in the posterior nasal cavity and nasopharynx (n=2), posterior nasoethmoidal tract (n=2), and maxillary sinus and nasal cavity (n=1). Compared with the brain stem, the soft tissue components of all lesions demonstrated isoattenuation on precontrast CT scans, slight hypointensity on T1-weighted MR images, and hyperintensity on T2-weighted MR images. On contrast-enhanced MR images, heterogeneous enhancement with marked peripheral enhancement was seen in two and homogeneous moderate enhancement in one. All lesions contained centrally located radiodense materials on CT scans, the shape of which was multiple clustered in three, single nodular in one, and single large lobulated in one.
Although rare, metaplastic ossification can occur within nasal polyps. The possibility of its diagnosis may be raised when one sees a benign-looking sinonasal mass with centrally located radiodense materials on CT scans. MR imaging may be useful when mycetoma or inverted papilloma cannot be ruled out on CT scans.
鼻息肉中骨化性化生是一种罕见的现象。本研究旨在回顾分析伴有骨化性化生的鼻息肉的 CT(计算机断层扫描)和磁共振(MRI)成像表现。
回顾性分析了 5 例经手术证实为伴有骨化性化生的鼻息肉患者的 CT(n=5)和 MRI(n=3)图像。记录了骨化性化生的位置和形态特征。
所有病变均表现为分叶状(n=3)、卵圆形(n=1)或哑铃状(n=1)的良性肿块,平均大小为 3.7cm(范围 2.4-6.5cm),单侧位于后鼻腔和鼻咽部(n=2)、后鼻额管(n=2)和上颌窦及鼻腔(n=1)。与脑桥相比,所有病变在平扫 CT 上软组织成分呈等密度,T1 加权 MRI 图像上呈轻度低信号,T2 加权 MRI 图像上呈高信号。增强 MRI 上,2 例呈不均匀强化,可见明显的周边强化,1 例呈均匀中度强化。所有病变在 CT 上均可见中央位置的放射性致密物质,其形态为 3 例呈多发簇状,1 例呈单发结节状,1 例呈单发大分叶状。
尽管罕见,但鼻息肉内可发生骨化性化生。当看到 CT 扫描上呈良性表现的鼻窦肿块且中央有放射性致密物质时,可能会考虑到该病的诊断。当 CT 扫描不能排除真菌球或内翻性乳头状瘤时,MRI 可能会有所帮助。