Pratt Kendra Covington, Hicks John, English Jeryl D, Bussa Harry I, Flaitz Catherine M, Powers John M
Department of Pathology, MC1-2261, Texas Children's Hospital, 6621 Fannin St., Houston, TX 77030-2313, USA.
Am J Dent. 2010 Jun;23(3):179-84.
To examine in vitro orthodontic bonding sealants combined with daily fluoride (NaF) rinse on caries-like lesion depths.
Permanent molar teeth (n = 40) were randomly divided into four treatment groups: 1: Pro-Seal, 2: Light Bond, 3: Pro-Seal with NaF rinsing, and 4: Light Bond with NaF rinsing. Orthodontic sealant material was placed on buccal surfaces of each group and surrounded by acid-resistant varnish on the buccal and a control window on the lingual. Each group underwent synthetic saliva rinsing and lesion initiation. Groups 3 and 4 were subjected to 0.05% NaF for 1 minute per day. Artificial caries were created in vitro. The specimens in each treatment group were sectioned and mean lesion depth was assessed with polarized light microscopy (water imbibition). Lesion depth was compared among the treament groups using ANOVA and Duncan's Multiple Range Test.
The ProSeal and Light Bond treatment groups exhibited significant reductions in mean lesion depths as compared to the controls (P < 0.05). ProSeal with NaF rinsing and Light Bond with NaF rinsing treatment groups exhibited significant reductions in mean lesion depth when compared to Pro Seal and Light Bond treatment without fluoride rinsing and controls (P < 0.05). The enamel-resin interfaces of all treatment groups were intact and exhibited no caries-like lesion formation.
研究体外正畸粘结密封剂联合每日使用含氟（NaF）漱口水对类龋损深度的影响。
将40颗恒牙随机分为四个治疗组：1：Pro - Seal；2：Light Bond；3：Pro - Seal联合NaF漱洗；4：Light Bond联合NaF漱洗。在每组牙齿的颊面放置正畸密封剂材料，并在颊面用抗酸漆包围，舌面设置对照窗口。每组进行人工唾液冲洗并引发龋损。第3组和第4组每天使用0.05%的NaF漱洗1分钟。在体外制造人工龋。对每个治疗组的标本进行切片，并用偏光显微镜（吸水法）评估平均龋损深度。使用方差分析和邓肯多重极差检验比较各治疗组之间的龋损深度。
与对照组相比，ProSeal和Light Bond治疗组的平均龋损深度显著降低（P < 0.05）。与未进行氟漱洗的Pro Seal和Light Bond治疗组及对照组相比，ProSeal联合NaF漱洗和Light Bond联合NaF漱洗治疗组的平均龋损深度显著降低（P < 0.05）。所有治疗组的釉质 - 树脂界面均完整，未出现类龋损形成。
