降低新生儿重症监护病房的医院感染率
Reducing nosocomial infections in neonatal intensive care.
作者信息
Rogers Eileen, Alderdice Fiona, McCall Emma, Jenkins John, Craig Stanley
机构信息
Neonatal Intensive Care Outcomes, Research & Evaluation Group, NICORE Office, Division of Maternal & Child Health, Institute of Clinical Science, Queen's University Belfast, Belfast, Northern Ireland.
出版信息
J Matern Fetal Neonatal Med. 2010 Sep;23(9):1039-46. doi: 10.3109/14767050903387029.
BACKGROUND
Nosocomial infection is a common problem in neonatal intensive care. A pilot quality improvement initiative focussing on hand hygiene and aimed at reducing nosocomial infection in very low birth weight (VLBW) infants was introduced in five Neonatal Intensive Care Units.
METHODS
Line associated laboratory confirmed bloodstream infection (LCBSI) and ventilator associated pneumonia (VAP) were chosen as main outcome measures.
RESULTS
In VLBW infants, the rate of line associated LCBSI per 1000 central venous catheter days fell by 24%. The rate of VAP per 1000 ventilator days in VLBW infants fell by 38%. Pre- and post-intervention questionnaires showed a statistically significant increase in use of alcohol-based gels and increased knowledge of hand hygiene.
背景
医院感染是新生儿重症监护中的常见问题。一项以手部卫生为重点、旨在降低极低出生体重（VLBW）婴儿医院感染率的试点质量改进举措在五个新生儿重症监护病房推行。
方法
将导管相关实验室确诊血流感染（LCBSI）和呼吸机相关性肺炎（VAP）选为主要结局指标。
结果
在VLBW婴儿中，每1000个中心静脉导管日的导管相关LCBSI发生率下降了24%。VLBW婴儿中每1000个呼吸机日的VAP发生率下降了38%。干预前后的问卷调查显示，酒精基凝胶的使用有统计学意义的增加，且手部卫生知识有所增加。
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