Department of Dermatology, University of Regensburg, Germany.
J Dtsch Dermatol Ges. 2010 Dec;8(12):968-76. doi: 10.1111/j.1610-0387.2010.07495.x. Epub 2010 Aug 13.
As a result of both the better understanding of complex plasma phenomena and the development of new plasma sources in the past few years, plasma medicine has developed into an innovative field of research showing high potential. While thermal plasmas have long been used in various medical fields (for instance for cauterization and sterilization of medical instruments), current research mainly focuses on application of non-thermal plasmas. Experiments show that cold atmospheric plasmas (CAPs) allow efficient, contact-free and painless disinfection, even in microscopic openings, without damaging healthy tissue. Plasmas influence biochemical processes and offer new possibilities for the selective application of individually designable medically active substances. In dermatology, new horizons are being opened for wound healing, tissue regeneration, therapy of skin infections, and probably many more diseases. First clinical trials show the efficacy and tolerability of plasma in treating infected chronic wounds. A major task will be the introduction of plasma into clinical medicine and, simultaneously, the further investigation of the mechanisms of action of plasma at the cellular level.
近年来，由于对复杂等离子体现象的更好理解和新型等离子体源的发展，等离子体医学已经发展成为一个具有高潜力的创新研究领域。虽然热等离子体在许多医学领域（例如，用于医疗仪器的烧灼和消毒）中已经得到了长期应用，但目前的研究主要集中在非热等离子体的应用上。实验表明，冷大气压等离子体（CAP）允许高效、非接触和无痛的消毒，即使在微小的开口处也能进行，而不会损坏健康组织。等离子体影响生化过程，并为选择性应用可单独设计的医用活性物质提供了新的可能性。在皮肤病学中，为伤口愈合、组织再生、皮肤感染治疗以及可能更多的疾病治疗开辟了新的前景。首次临床试验表明等离子体治疗感染性慢性伤口的疗效和耐受性。一项主要任务将是将等离子体引入临床医学，同时在细胞水平上进一步研究等离子体的作用机制。
