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鼻部外用药依从性——变应性鼻炎患儿的评估。

Compliance with topical nasal medication--an evaluation in children with rhinitis.

机构信息

Department of Paediatrics, Yong Loo Lin School of Medicine, National University Health System, Singapore.

出版信息

Pediatr Allergy Immunol. 2010 Dec;21(8):1146-50. doi: 10.1111/j.1399-3038.2010.01015.x. Epub 2010 Aug 16.

DOI:10.1111/j.1399-3038.2010.01015.x
PMID:20718924
Abstract

It is our impression that children with rhinitis often dislike or struggle with the administration of topical nasal sprays and drops. This study aims to investigate children's acceptance of topical nasal sprays/drops, and to identify patient factors that may affect their acceptance. An interview (by WYZI) questionnaire survey was carried out on parents/guardians of children aged 1-15 with rhinitis, where information on the diagnosis and treatment, patients' use and responses to these medications, and their preferred treatment routes were collected. Two hundred questionnaires were completed, of which 194 were valid for analysis. The mean age of patients was 7.54 yr; male to female ratio was 1:1.6, and Chinese made up the majority (62.4%). About one quarter (24.7%) of children disliked the use of topical nasal sprays/drops sufficiently to affect compliance with the medication. Furthermore, of those who could indicate their preferred route of drug administration (n = 75), 73% indicated a preference for oral medication, while only 11% preferred the nasal route. Topical nasal sprays/drops were more acceptable in older children (7-15 yr) compared to the younger ones (1-6 yr) (OR = 2.383, CI 1.223-4.644). The acceptance of nasal sprays/drops was not associated with gender, ethnic group, concurrent use by other family members, length and amount of usage, and the response to therapy. A substantial proportion of children prescribed topical nasal sprays/drops did not find it acceptable. Age played a significant factor to the acceptance of the use of topical nasal sprays/drops.

摘要

我们的印象是,患有鼻炎的儿童通常不喜欢或难以接受局部鼻腔喷雾剂和滴剂的治疗。本研究旨在调查儿童对局部鼻腔喷雾剂/滴剂的接受程度,并确定可能影响其接受程度的患者因素。我们对 1-15 岁患有鼻炎的儿童的父母/监护人进行了访谈(由 WYZI 进行)问卷调查,收集了关于诊断和治疗、患者使用这些药物的情况和反应以及他们首选的治疗途径的信息。共完成了 200 份问卷,其中 194 份有效进行分析。患者的平均年龄为 7.54 岁;男女比例为 1:1.6,以汉族为主(62.4%)。约四分之一(24.7%)的儿童非常不喜欢使用局部鼻腔喷雾剂/滴剂,以至于影响了他们对药物的依从性。此外,在那些能够表明他们首选的给药途径的儿童中(n=75),73%的儿童表示更喜欢口服药物,而只有 11%的儿童更喜欢鼻腔途径。与年龄较小的(1-6 岁)儿童相比,年龄较大的(7-15 岁)儿童更容易接受鼻腔喷雾剂/滴剂(OR=2.383,CI 1.223-4.644)。鼻腔喷雾剂/滴剂的接受程度与性别、种族、其他家庭成员同时使用、使用时间和使用量以及对治疗的反应无关。相当一部分被处方使用局部鼻腔喷雾剂/滴剂的儿童认为其不可接受。年龄是影响儿童接受局部鼻腔喷雾剂/滴剂使用的一个重要因素。

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