Stupiansky Nathan W, Rosenthal Susan L, Wiehe Sarah E, Zimet Gregory D
Section of Adolescent Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Sex Health. 2010 Sep;7(3):304-9. doi: 10.1071/SH09127.
In the USA, the human papillomavirus (HPV) vaccine is currently licensed for 9-26-year-old females, but licensure for women over 26 years is being considered. The aim of the current study was to investigate the association of sociodemographic and health-related factors to HPV vaccine acceptability among adult women.
The current study utilised a nationally representative sample of women (n = 1323) aged 27-55 living in the USA, with an oversampling of black and Latina women. A multiple item measure of HPV vaccine acceptability across varying cost and location-of-availability (clinic only v. any local pharmacy) conditions was the main outcome measure. General linear modelling was used to analyse the association of vaccine cost, location availability, and sociodemographic and health-related variables with vaccine acceptability.
Vaccine cost had the strongest association with acceptability [F (2, 1249) = 832.1; P < 0.0001]; however, factors such as religiosity, political views, a history of various negative sexual health outcomes and previous flu shot receipt were also associated with acceptability. Location availability had a statistically significant but modest effect, with a slight preference shown for health clinic availability.
Adult women had generally high levels of HPV vaccine acceptability, but were greatly influenced by cost of the vaccine. Women who had experienced negative sexual health outcomes due to HPV-specific infection rated the vaccine as more acceptable, perhaps due to distress associated with those outcomes.
在美国,人乳头瘤病毒(HPV)疫苗目前已获批用于9至26岁的女性,但正在考虑批准用于26岁以上的女性。本研究的目的是调查社会人口统计学和健康相关因素与成年女性HPV疫苗可接受性之间的关联。
本研究采用了美国27至55岁女性的全国代表性样本(n = 1323),其中黑人和拉丁裔女性为过度抽样。在不同成本和可获得地点(仅诊所与任何当地药房)条件下,对HPV疫苗可接受性的多项测量是主要结果指标。使用一般线性模型分析疫苗成本、可获得地点以及社会人口统计学和健康相关变量与疫苗可接受性之间的关联。
疫苗成本与可接受性的关联最为强烈[F(2, 1249) = 832.1;P < 0.0001];然而,宗教信仰、政治观点、各种负面性健康结果的病史以及以前是否接种流感疫苗等因素也与可接受性有关。可获得地点有统计学显著但适度的影响,对健康诊所的可获得性略有偏好。
成年女性对HPV疫苗的可接受性普遍较高,但受疫苗成本的影响很大。因HPV特异性感染而经历负面性健康结果的女性认为该疫苗更可接受,这可能是由于与这些结果相关的困扰。