Walzer Chris, Goritz Frank, Hermes Robert, Nathan Sen, Kretzschmar Petra, Hildebrandt Thomas
Research Institute of Wildlife Ecology, University of Veterinary Medicine, Savoyenstrasse 1, A-1160 Vienna, Austria.
J Zoo Wildl Med. 2010 Mar;41(1):115-20. doi: 10.1638/2009-0150.1.
This paper reports in detail, for the first time, on two anesthetic procedures performed on a 15-yr-old, 530 kg, adult male Sumatran rhinoceros (Dicerorhinus sumatrensis). The anesthetic procedures were carried out in order to perform semen collection via electro-ejaculation, using well-established methods, and in order to examine and sample bilateral corneal opacities. Anesthesia for the first procedure was induced with a combination of 5 mg (0.0094 mg/kg) butorphanol tartrate and 5 mg (0.0094 mg/kg) detomidine hydrochloride administered intramuscularly. Subsequently, 0.74 mg (0.0014 mg/kg) etorphine and 3 mg (0.0057 mg/kg) acepromazine, with an additional 1.5 mg butorphanol (0.0028 mg/kg) and 1.5 mg (0.0028 mg/kg) detomidine, were administered intramuscularly. The second procedure was carried out using an intramuscular combination of butorphanol (0.019 mg/kg) and detomidine (0.019 mg/kg), followed by etorphine (0.0023 mg/kg) and acepromazine (0.009 mg/ kg). During the second procedure, the depth of anesthesia was managed with very small, supplemental intravenous doses of 50 mg ketamine (0.094 mg/kg). Sequential arterial blood gas analysis demonstrated respiratory acidosis with hypoxemia. Heart rate and respiratory rate ranged between 60-74 beats per minute (bpm), and 10-20 breaths per minute, respectively. Reversal after 100 min, with the intravenous administration of 150 mg (0.28 mg/kg) naltrexone and intravenous 20 mg (0.038 mg/kg) atipamezole, was uneventful and rapid, with the animal standing after 2 min. This combination provides satisfactory general anesthesia in this critically endangered species and will facilitate veterinary management of this species in captivity.
本文首次详细报道了对一头15岁、体重530千克的成年雄性苏门答腊犀牛(双角犀属苏门答腊种)实施的两种麻醉程序。实施这些麻醉程序的目的,一是采用成熟方法通过电刺激采精,二是检查双侧角膜混浊并取样。第一次手术的麻醉诱导采用肌肉注射5毫克(0.0094毫克/千克)酒石酸布托啡诺和5毫克(0.0094毫克/千克)盐酸右美托咪定的组合。随后,肌肉注射0.74毫克(0.0014毫克/千克)埃托啡和3毫克(0.0057毫克/千克)乙酰丙嗪,并额外注射1.5毫克布托啡诺(0.0028毫克/千克)和1.5毫克(0.0028毫克/千克)右美托咪定。第二次手术采用肌肉注射布托啡诺(0.019毫克/千克)和右美托咪定(0.019毫克/千克)的组合,随后注射埃托啡(0.0023毫克/千克)和乙酰丙嗪(0.009毫克/千克)。在第二次手术期间,通过静脉注射极少量(50毫克,0.094毫克/千克)氯胺酮来维持麻醉深度。连续动脉血气分析显示存在呼吸性酸中毒并伴有低氧血症。心率和呼吸频率分别在每分钟60 - 74次心跳(bpm)和每分钟10 - 20次呼吸之间。100分钟后,通过静脉注射150毫克(0.28毫克/千克)纳曲酮和静脉注射20毫克(0.038毫克/千克)阿替美唑进行苏醒,过程顺利且迅速,动物在2分钟后站立。这种组合为这种极度濒危物种提供了令人满意的全身麻醉,并将有助于圈养该物种的兽医管理。