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爱尔兰生育患者中选定的卵子、血液及器官/组织捐赠特征的描述性研究。

A descriptive study of selected oocyte, blood and organ/tissue donation features among fertility patients in Ireland.

作者信息

Sills E Scott, Collins Gary S, Walsh David J, Omar Ahmed B, Salma Umme, Walsh Anthony P H

机构信息

Sims IVF/Department of Obstetrics and Gynaecology, School of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.

出版信息

Hum Fertil (Camb). 2010;13(2):98-104. doi: 10.3109/14647273.2010.491573.

Abstract

OBJECTIVE

Anonymous oocyte donation and participation in organ and blood/tissue donation programmes were studied specifically among Irish fertility patients.

METHODS

An anonymous questionnaire measured patient perceptions of, and participation in, blood/organ/tissue donor programmes, and to record opinion on anonymous donor oocyte compensation.

RESULTS

A total of 337 patents were sampled; 56.7% had no children. None had participated in a donor oocyte programme either as donor or recipient. At baseline, 19.6% had previous in vitro fertilisation experience, more than one-third (35.9%) had donated blood anonymously, 19.9% were organ/tissue donors and 52.2% indicated that anonymous oocyte donors should receive some compensation. We found patients with infertility for extended periods were more likely to view oocyte donation favourably, compared to those with infertility of shorter durations (p = 0.022, by Krusksal-Wallis Rank Sum test). Average recommended compensation for anonymous oocyte donor was euro 2177 (range euro 200-euro 9500), and most (77.2%) favoured confidential protections for recipient and donor identity.

CONCLUSION

This is the first investigation of blood and organ/tissue donation features among fertility patients in Ireland; the rate of blood donation in this group was more than 10 times higher than in the general Irish population. Protection of anonymity for both donors and recipients was supported by most patients, even opponents of compensated anonymous donation. Further studies should clarify patient perceptions about oocyte donation as a function of involvement in organ/tissue procurement programmes and blood banks.

摘要

目的

专门针对爱尔兰生育患者研究匿名卵子捐赠以及参与器官和血液/组织捐赠项目的情况。

方法

通过一份匿名问卷来衡量患者对血液/器官/组织捐赠项目的看法及参与情况,并记录对匿名捐赠卵子补偿的意见。

结果

共抽取了337名患者样本;56.7%没有孩子。无人作为捐赠者或接受者参与过卵子捐赠项目。基线时,19.6%有过体外受精经历,超过三分之一(35.9%)曾匿名献血,19.9%是器官/组织捐赠者,52.2%表示匿名卵子捐赠者应获得一定补偿。我们发现,与不孕时间较短的患者相比,长期不孕的患者更倾向于看好卵子捐赠(通过Krusksal-Wallis秩和检验,p = 0.022)。匿名卵子捐赠者的平均推荐补偿金额为2177欧元(范围为200欧元至9500欧元),大多数(77.2%)支持对接受者和捐赠者身份进行保密保护。

结论

这是对爱尔兰生育患者血液及器官/组织捐赠特征的首次调查;该群体的献血率比爱尔兰普通人群高出10倍以上。大多数患者,甚至是有偿匿名捐赠的反对者,都支持对捐赠者和接受者的匿名性进行保护。进一步的研究应阐明患者对卵子捐赠的看法与参与器官/组织采购项目和血库之间的关系。

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