Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK.State agency: Infectology Center of Latvia, Linezera street 3, Riga, LV-1006, Latvia.Department of Zoology, University of Oxford, Oxford, UK.Department of Infectious Disease Epidemiology, Imperial College London, St. Mary's Hospital, London W2 1PG, UK.Institute of Biological and Environmental Sciences, Zoology Building, Aberdeen AB24 2TZ, UK.Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.
Environ Microbiol. 2011 Jan;13(1):184-192. doi: 10.1111/j.1462-2920.2010.02319.x. Epub 2010 Aug 16.
The geographic patterns of transmission opportunities of vector-borne zoonoses are determined by a complex interplay between the migration patterns of the host and the vector. Here we examine the impact of host migration on the spread of a tick-borne zoonotic disease, using Lyme Borreliosis (LB) spirochaetal species in Europe. We demonstrate that the migration of the LB species is dependent on and limited by the migration of their respective hosts. We note that populations of Borrelia spp. associated with birds (Borrelia garinii and B. valaisiana) show limited geographic structuring between countries compared with those associated with small mammals (Borrelia afzelii), and we argue that this can be explained by higher rates of migration in avian hosts. We also show the presence of B. afzelii strains in England and, through the use of the multi-locus sequence analysis scheme, reveal that the strains are highly structured. This pattern in English sites is very different from that observed at the continental sites, and we propose that these may be recent introductions.
虫媒传染病传播机会的地理模式是由宿主和媒介的迁移模式之间的复杂相互作用决定的。在这里，我们使用欧洲的莱姆病螺旋体物种来研究宿主迁移对蜱传动物传染病传播的影响。我们证明 LB 物种的迁移依赖于并受其各自宿主迁移的限制。我们注意到，与小型哺乳动物（阿菲希氏螺旋体）相关的鸟（加氏疏螺旋体和贝氏疏螺旋体）相关的 Borrelia spp.种群在国家之间的地理结构有限，我们认为这可以通过鸟类宿主中更高的迁移率来解释。我们还表明，在英格兰存在阿菲希氏螺旋体菌株，并通过使用多位点序列分析方案，揭示了这些菌株具有高度的结构。英国各站点的这种模式与大陆各站点观察到的模式非常不同，我们提出这些可能是最近的引入。
