Poroshin K K, Kudriavtsev B N
Arkh Patol. 1987;49(7):64-7.
Brief literature data on clinico-morphologic manifestation of retroperitoneal paraganglioma and its differential diagnosis with ectopic pheochromocytoma is presented. A female 31-year old patient is described with a rapid growth of retroperitoneal neoplasm and a concomitant increase of arterial blood pressure, first paroxysmal and then permanent. After the tumor excision (10 X 13 X 16 cm in size), not connected with the adrenal, the blood pressure recovered. The morphologic study provided the evidence for malignant paraganglioma different from ectopic pheochromocytoma in structural polymorphism and small size of neurosecretory granules. The arterial blood pressure increase is suggested to be due to tumor compression on the left kidney vessels.
本文介绍了腹膜后副神经节瘤临床形态学表现及其与异位嗜铬细胞瘤鉴别诊断的简要文献资料。描述了一名31岁女性患者，其腹膜后肿瘤迅速生长，同时动脉血压升高，起初为阵发性，后转为持续性。在切除与肾上腺无关的肿瘤（大小为10×13×16厘米）后，血压恢复正常。形态学研究证实该肿瘤为恶性副神经节瘤，在结构多态性和神经分泌颗粒较小方面与异位嗜铬细胞瘤不同。动脉血压升高提示是由于肿瘤压迫左肾血管所致。
