Psychiatry Department, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India.
Am J Ther. 2012 May;19(3):e118-9. doi: 10.1097/MJT.0b013e3181ebb268.
Clozapine has been reported to cause agranulocytosis, neutropenia, and leucopenia that usually occur within 18 weeks of initiation of treatment. We report a case of delayed onset leucopenia after 11 years of treatment with clozapine, which reversed within a few days after discontinuation of medication.
氯氮平据报道可引起粒细胞缺乏症、中性粒细胞减少症和白细胞减少症,通常在开始治疗后 18 周内发生。我们报告了一例氯氮平治疗 11 年后出现的迟发性白细胞减少症,停药数天后自行恢复。