Jennings Lorraine, Schmults Chrysalyne D
Mohs Micrographic Surgery Center, Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
J Clin Aesthet Dermatol. 2010 Apr;3(4):39-48.
Cutaneous squamous cell carcinoma is an increasing public health concern, representing the second most common cancer in the United States. High-risk cutaneous squamous cell carcinoma represents a subgroup of this disease, where patients are at higher risk of metastasis and death. To date, there are no accepted criteria for defining or managing these patients. This review discusses the current state of knowledge of high-risk cutaneous squamous cell carcinoma and outlines reasonable management strategies based on available data.
皮肤鳞状细胞癌日益引起公众对健康的关注,是美国第二大常见癌症。高危皮肤鳞状细胞癌是该疾病的一个亚组,这类患者发生转移和死亡的风险更高。迄今为止,尚无公认的定义或管理这些患者的标准。本综述讨论了高危皮肤鳞状细胞癌的当前知识状况,并根据现有数据概述了合理的管理策略。