Bari Omar, Cohen Philip R
School of Medicine, University of California, San Diego.
Department of Dermatology, University of California, San Diego.
Cureus. 2017 Mar 28;9(3):e1122. doi: 10.7759/cureus.1122.
Tonsillar squamous cell carcinoma, which represents 10% of head and neck malignancies, rarely manifests with cutaneous metastases; to date, only three prior patients with tonsillar squamous cell carcinoma have been reported to develop cutaneous metastases. We describe the clinical features of a 59-year-old man with squamous cell carcinoma of the tonsil who developed cutaneous metastases within his prior radiation port and review the literature of prior patients with cutaneous metastases from tonsillar squamous cell carcinoma. The PubMed database was searched for the following keywords: carcinoma, cutaneous, metastasis, squamous, and tonsil. The papers generated by the search and their references were reviewed. Cutaneous metastasis from tonsillar cancer is rare but should be considered in patients with a history of a squamous cell carcinoma of the tonsil; new skin lesions, both overlying the visceral malignancy and at more distant sites, should be biopsied since prognosis in these patients is poor. Management has thus far been palliative and should be individualized to the patient.
扁桃体鳞状细胞癌占头颈部恶性肿瘤的10%,很少出现皮肤转移;迄今为止,仅有3例先前患扁桃体鳞状细胞癌的患者被报道发生皮肤转移。我们描述了一名59岁扁桃体鳞状细胞癌男性患者在其先前放疗区域内发生皮肤转移的临床特征,并回顾了先前患扁桃体鳞状细胞癌皮肤转移患者的文献。在PubMed数据库中搜索了以下关键词:癌、皮肤、转移、鳞状、扁桃体。对搜索生成的论文及其参考文献进行了综述。扁桃体癌的皮肤转移很少见,但有扁桃体鳞状细胞癌病史的患者应予以考虑;应切除覆盖内脏恶性肿瘤部位及更远处新出现的皮肤病变,因为这些患者的预后较差。迄今为止,治疗一直是姑息性的,应根据患者个体情况进行。