Korotaev G M, Sheprinskiĭ P E, Osmokesku K I
Khirurgiia (Mosk). 1991 May(5):19-23.
The article generalizes the result of experimental study of the features of hemolymphodynamics, toxic properties of biological body fluids, and microbiological findings in peritonitis. Experiments were conducted on 24 dogs. The development of the pyogenic process was visually studied. For this purpose the opened abdominal cavity was placed in a specially constructed transparent chamber in which a temperature of 37 /*C was maintained. Portal blood flow intensified and lymph production in the abdominal cavity reduced in the initial phase of peritonitis. Later lymph production increased while the portal blood flow decreased. The purulent process may develop according to two variants. In the first variant the functional activity of the liver is maintained and its toxic products and microorganisms are detoxified; the second variant the detoxification function of the liver is disturbed, the bacteria penetrate the peripheral blood, the production and flow of lymph in the thoracic duct increase sharply. The efficacy of external drainage of the duct and lymphosorption is much higher in the second variant of peritonitis development than in the first variant.
本文总结了关于腹膜炎血淋巴动力学特征、生物体液毒性特性及微生物学研究结果的实验研究成果。实验在24只犬身上进行。对化脓过程的发展进行了直观研究。为此,将打开的腹腔置于一个特制的透明腔室中,该腔室保持37℃的温度。腹膜炎初期门静脉血流增强,腹腔淋巴生成减少。随后淋巴生成增加,而门静脉血流减少。化脓过程可能按两种方式发展。第一种方式中,肝脏的功能活性得以维持,其毒性产物和微生物被解毒;第二种方式中,肝脏的解毒功能受到干扰,细菌进入外周血,胸导管中淋巴的生成和流动急剧增加。在腹膜炎发展的第二种方式中,导管外部引流和淋巴吸附的效果比第一种方式高得多。