Nikolaeva E V
Vestn Khir Im I I Grek. 1985 Oct;135(10):35-8.
Activity of alkaline phosphatase was studied in blood and lymph of 52 dogs with experimental peritonitis and in 26 patients with the drained thoracic duct and in 26 patients without lymphodrainage. Pronounced enzyme intoxication was revealed. Under physiological conditions alkaline phosphatase is transported by both blood and lymphatic bed. In peritonitis the lymphatic route of the enzyme transport gets considerably greater. Drainage of the thoracic duct gives good detoxicating effect (decreased alkaline phosphatase activity).
对52只患有实验性腹膜炎的犬的血液和淋巴、26名接受胸导管引流的患者以及26名未进行淋巴引流的患者的碱性磷酸酶活性进行了研究。结果显示存在明显的酶中毒现象。在生理条件下,碱性磷酸酶通过血液和淋巴系统进行转运。在腹膜炎时,酶的淋巴转运途径显著增加。胸导管引流具有良好的解毒效果(碱性磷酸酶活性降低)。