用胶原酶处理大鼠肝脏后，肝素可释放的三酰甘油脂肪酶活性完全丧失。
Complete loss of heparin-releasable triacylglycerol lipase activity after collagenase treatment of the rat liver.
作者信息
Thomas J, Debeer L J, Mannaerts G P
出版信息
Biochem J. 1978 Apr 15;172(1):177-9. doi: 10.1042/bj1720177.
Abstract
Lipolytic activity at pH 8.5-9.5 was lowered by approx. 80% in homogenates from livers perfused with collagenase or heparin. No heparin-releasable lipase activity was detected in hepatocytes isolated by collagenase treatment. It is concluded that crude collagenase completely inactivates the plasma-membrane-bound heparin-releasable lipase.
摘要
在pH 8.5 - 9.5条件下，用胶原酶或肝素灌注肝脏的匀浆中的脂解活性降低了约80%。经胶原酶处理分离得到的肝细胞中未检测到可被肝素释放的脂肪酶活性。结论是粗制胶原酶可使与质膜结合的可被肝素释放的脂肪酶完全失活。
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Uptake of chyle cholesterol esters and intact triglycerides by suspended hepatocytes.悬浮肝细胞对乳糜微粒胆固醇酯和完整甘油三酯的摄取。
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