Balasubramanian Karthikeyan, Kalsi Pratipal, Greenough Charles G, Kuskoor Seetharam Manjunath Prasad
Department of Trauma, Regional Spinal Cord Injuries Centre, James Cook University Hospital, Middlesbrough, UK.
Br J Neurosurg. 2010 Aug;24(4):383-6. doi: 10.3109/02688697.2010.505987.
Cauda equina syndrome (CES) is a neurological syndrome presenting with non-specific symptoms and signs that often leads to diagnostic confusion and delay. Acute onset CES is a surgical emergency. The common aetiology is a prolapsed lumbar disc. If the diagnosis is missed, it can have devastating consequences for the patient and a high financial cost to healthcare providers. The objective of this study was to evaluate the efficacy of clinical assessment in clinching the diagnosis. Eighty patients who underwent urgent clinical assessment and magnetic resonance imaging (MRI) for suspected CES over a 1-year period (from January 1st 2008 to 31 December 2008) were included in the study. Fifteen of these patients had a CES and underwent urgent lumbar discectomy and decompression. Medical notes and MRI scans of all these patients were reviewed. The presenting symptoms and signs were analysed against a positive MRI scan. Chi-square test with Yates correction was used to test association of each clinical symptom and sign for a positive MRI. In this study, only 18.8% of assessed patients had a CES producing compression seen on the MRI. Presence of saddle sensory deficit was the only clinical feature with a statistically significant association with MRI positive CES (p = 0.03). This series shows that saddle sensory deficit has a higher predictive value than other clinical features in diagnosing a CES. However, as there is no symptom or sign which has an absolute predictive value in establishing the diagnosis of CES, any patient in whom a reasonable suspicion of CES arises must undergo urgent MRI to exclude this diagnosis.
马尾综合征(CES)是一种神经系统综合征,表现为非特异性症状和体征,常导致诊断混淆和延误。急性发作的CES是一种外科急症。常见病因是腰椎间盘突出。如果漏诊,对患者可能会造成灾难性后果,对医疗服务提供者来说也会产生高昂的经济成本。本研究的目的是评估临床评估在确诊中的有效性。本研究纳入了80例在1年期间(从2008年1月1日至2008年12月31日)因疑似CES接受紧急临床评估和磁共振成像(MRI)检查的患者。其中15例患者患有CES并接受了紧急腰椎间盘切除术和减压术。对所有这些患者的病历和MRI扫描进行了回顾。根据MRI扫描阳性结果分析所呈现的症状和体征。采用经Yates校正的卡方检验来检验每种临床症状和体征与MRI阳性结果之间的相关性。在本研究中,只有18.8%的评估患者在MRI上显示有导致压迫的CES。鞍区感觉缺失是唯一与MRI阳性CES有统计学显著相关性的临床特征(p = 0.03)。该系列研究表明,在诊断CES时,鞍区感觉缺失比其他临床特征具有更高的预测价值。然而,由于在确诊CES时没有任何症状或体征具有绝对的预测价值,任何合理怀疑患有CES的患者都必须接受紧急MRI检查以排除该诊断。