Montano Nicola, Doglietto Francesco, Lauriola Libero, Signorelli Francesco, Pallini Roberto
Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy.
Br J Neurosurg. 2010 Aug;24(4):495-6. doi: 10.3109/02688691003675226.
Solitary Fibrous Tumour (SFT) is a rare tumour occurring mainly in the pleural cavity, with less than 100 cases reported in the Central Nervous System, where it typically presents as a meningeal-based lesion. We describe the case of a SFT located in the fourth ventricle and briefly review the pertinent literature.
A 61-year-old man presented with a 6-month-history of dizziness, nausea and gait imbalance. Brain magnetic resonance imaging revealed a contrast enhancing, space occupying lesion in the fourth ventricle, with no dural attachment. The patient underwent a sub-occipital craniectomy and total excision of the lesion. Histological examination documented a SFT. The patient is recurrent free at the 2-year follow-up.
Although uncommon, SFT should always be included in the differential diagnosis of intraventricular tumours. SFTs of the fourth ventricle are usually benign tumours. Surgery remains the treatment of choice.
孤立性纤维瘤(SFT)是一种罕见肿瘤,主要发生于胸腔,中枢神经系统报道病例不足100例,在中枢神经系统中通常表现为以脑膜为基底的病变。我们描述一例位于第四脑室的SFT病例并简要回顾相关文献。
一名61岁男性,有6个月头晕、恶心及步态不稳病史。脑部磁共振成像显示第四脑室有一强化的占位性病变,无硬脑膜附着。患者接受了枕下开颅手术及病变全切术。组织学检查证实为SFT。患者在2年随访时无复发。
尽管不常见,但SFT应始终纳入脑室内肿瘤的鉴别诊断。第四脑室SFT通常为良性肿瘤。手术仍然是首选治疗方法。