Boogaarts Hieronymus D, Verbeek André L M, Bartels Ronald H M A
Department of Neurosurgery, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6500 HB Nijmegen, The Netherlands.
Clin Neurol Neurosurg. 2010 Nov;112(9):791-3. doi: 10.1016/j.clineuro.2010.07.002. Epub 2010 Aug 19.
Antiplatelet therapy is often instituted after cardiovascular or neurological ischemic events. In general, discontinuation of the antiplatelet medication for several days is warranted previous to surgery. However, discontinuation can lead to ischemic events. For some forms of surgery, the risks of an ischemic event, and especially, its consequences do not outweigh the benefit of discontinuation of the antiplatelet therapy. Retrospective analysis was done of a cohort of patients treated for carpal tunnel syndrome with special emphasis on postoperative hemorrhage in combination with antiplatelet medication.
Retrospective analysis of cohort consisting of 362 consecutive patients treated for carpal tunnel syndrome in the Neurosurgical Centre, Nijmegen was done.
In 362 patients 423 operations on carpal tunnel release were done. Thirty-one patients were on antiplatelet therapy, of which 6 did not discontinue the medication before surgery. The remaining patients stopped at least seven days before surgery. A postoperative hemorrhage did not occur in any of the 423 operations.
There seems no reasonable evidence that discontinuation of aspirin for carpal tunnel syndrome is justified. Bleeding complications are considered rare, moreover the impact of an ischemic cardiovascular or a cerebral event would be far more severe than that of postoperative hemorrhage in the wrist.
抗血小板治疗常在心血管或神经缺血性事件后开始。一般来说,手术前几天停用抗血小板药物是必要的。然而,停药可能导致缺血性事件。对于某些手术形式,缺血性事件的风险,尤其是其后果并不超过停用抗血小板治疗的益处。对一组接受腕管综合征治疗的患者进行回顾性分析,特别关注术后出血与抗血小板药物的联合情况。
对奈梅亨神经外科中心连续治疗的362例腕管综合征患者组成的队列进行回顾性分析。
362例患者进行了423次腕管松解手术。31例患者接受抗血小板治疗,其中6例在手术前未停药。其余患者在手术前至少停药7天。423次手术中均未发生术后出血。
似乎没有合理的证据表明因腕管综合征停用阿司匹林是合理的。出血并发症被认为很少见,此外,缺血性心血管或脑部事件的影响远比手腕术后出血严重得多。