Brunetti Stefania, Petri Gianfranco John, Lucchina Stefano, Garavaglia Guido, Fusetti Cesare
Stefania Brunetti, Gianfranco John Petri, Stefano Lucchina, Guido Garavaglia, Cesare Fusetti, Hand Surgery Unit, Department of Orthopaedics and Trauma Surgery, Ospedale Regionale Bellinzona e Valli, 6500 Bellinzona, Switzerland.
World J Orthop. 2013 Oct 18;4(4):299-302. doi: 10.5312/wjo.v4.i4.299. eCollection 2013.
To determine whether patients taking aspirin during carpal tunnel release had an increase of complications.
Between January 2008 and January 2010, 150 patients underwent standard open carpal tunnel release (CTR) under intravenous regional anaesthesia. They were divided into three groups: groups 1 and 2 were made of 50 patients each, on aspirin 100 mg/d for at least a year. In group 1 the aspirin was never stopped. In group 2 it was stopped at least 5 d before surgery and resumed 3 d after. Group 3 acted as a control, with 50 patients who did not take aspirin. The incidence of clinically significant per- or post-operative complications was recorded and divided into local and cardio-cerebro-vascular complications. Local complications were then divided into minor and major according to Page and Stern. Local haematomas were assessed at 2 d (before resuming aspirin in group 2) and 14 d (after resuming aspirin in group 2) postoperatively. Patients were reviewed at 2, 14 and 90 d after surgery.
There was no significant difference in the incidence of complications in the three groups. A total of 3 complications (2 major and 1 minor) and 27 visible haematomas were recorded. Two major complications were observed respectively in group 1 (non stop aspirin) and in group 3 (never antiaggregated). The minor complication, observed in one patient of group 2 (stop aspirin), consisted of a wound dehiscence, which only led to delayed healing. All haematomas were observed in the first 48 h, no haematoma lasted for more than 2 wk and all resolved spontaneously. A major haematoma (score > 20 cm(2)) was observed in 8 patients. A minor haematoma (score < 20 cm(2)) was recorded in 19 patients. All patients at 90 d after surgery were satisfied with the result in terms of relief of their preoperative symptoms. Major and minor haematomas did not impair hand function or require any specific therapy.
Our study demonstrates that continuation of aspirin did not increase the risk of complications. It is unnecessary to stop aspirin before CTR with good surgical techniques.
确定在腕管松解术中服用阿司匹林的患者并发症是否增加。
2008年1月至2010年1月期间,150例患者在静脉区域麻醉下接受标准开放性腕管松解术(CTR)。他们被分为三组:第1组和第2组各有50例患者,服用阿司匹林100mg/d至少一年。第1组阿司匹林从未停药。第2组在手术前至少停药5天,术后3天恢复用药。第3组作为对照组,有50例未服用阿司匹林的患者。记录临床显著的术中或术后并发症的发生率,并分为局部并发症和心脑血管并发症。然后根据佩奇和斯特恩的标准将局部并发症分为轻微和严重。在术后2天(第2组恢复服用阿司匹林前)和14天(第2组恢复服用阿司匹林后)评估局部血肿情况。术后2、14和90天对患者进行复查。
三组并发症发生率无显著差异。共记录到3例并发症(2例严重和1例轻微)以及27例可见血肿。在第1组(未停用阿司匹林)和第3组(从未进行抗凝血)中分别观察到2例严重并发症。在第2组(停用阿司匹林)的1例患者中观察到的轻微并发症为伤口裂开,仅导致愈合延迟。所有血肿均在最初48小时内观察到,没有血肿持续超过2周,且均自行消退。8例患者观察到严重血肿(评分>20cm²)。19例患者记录到轻微血肿(评分<20cm²)。所有患者术后90天时对术前症状缓解的结果均感到满意。严重和轻微血肿均未损害手部功能,也无需任何特殊治疗。
我们的研究表明,继续服用阿司匹林不会增加并发症风险。在采用良好手术技术的腕管松解术前无需停用阿司匹林。