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[布拉柴维尔-刚果大学医院中心胃肠病学与内科住院患者的乙型肝炎病毒血清学标志物]

[Serological markers of hepatitis B virus in hospitalized patients (Gastroenterology and Internal Medicine Service of the University Hospital Center of Brazzaville - Congo )].

作者信息

Ibara J R, Itoua-Ngaporo A, Maniez-Montreuil M, Dupressoir M V, Huart J J, Paris J C

机构信息

Service de Gastro-Entérologie et de Médecine Interne, Centre Hospitalier Universitaire, Brazzaville, Congo.

出版信息

Med Trop (Mars). 1991 Jan-Mar;51(1):9-13.

PMID:2072856
Abstract

The prevalence of serum markers of the hepatitis B virus was studied in 139 patients, 88 men and 51 women, at the Gastroenterology and Internal Medicine Department at the University Hospital in Brazzaville (Congo). The findings show that 125 individuals (89%), 79 men and 46 women, show signs of infection. Only 14 patients, 9 men and 5 women, show no hepatitis B virus markers. 64 individuals (46%) are carriers of Ag HBS, and among these, 23 (35.9%) are carriers of Ag HBe. Ac anti HBC was found 116 times (83.4%): 12 times by itself, and 16 times in association with Ac anti HBS. 43 individuals (30.9 %) are carriers of Ac anti HBS. Such high frequency of Ac anti HBS, whether or not accompanied by Ac anti HBC, argues in favor of the age of the infection. The study points out the high frequency of hepatitis B virus markers (89.8 %) compared with blood donors (7 to 9 %). This should incite government officials to set up some preventive procedures.

摘要

在刚果布拉柴维尔大学医院的胃肠病学和内科,对139名患者(88名男性和51名女性)进行了乙肝病毒血清标志物患病率的研究。研究结果显示,125人(89%),即79名男性和46名女性,有感染迹象。只有14名患者,即9名男性和5名女性,未显示乙肝病毒标志物。64人(46%)是乙肝表面抗原(Ag HBS)携带者,其中23人(35.9%)是乙肝e抗原(Ag HBe)携带者。抗乙肝核心抗体(Ac anti HBC)出现了116次(83.4%):单独出现12次,与抗乙肝表面抗体(Ac anti HBS)同时出现16次。43人(30.9%)是抗乙肝表面抗体携带者。抗乙肝表面抗体出现如此高的频率,无论是否伴有抗乙肝核心抗体,都表明感染时间较长。该研究指出,与献血者(7%至9%)相比,乙肝病毒标志物的频率很高(89.8%)。这应促使政府官员制定一些预防措施。

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