School of Biology, University of Nottingham, Nottingham, UK, NG7 2RD.
Trends Parasitol. 2010 Nov;26(11):524-9. doi: 10.1016/j.pt.2010.07.001. Epub 2010 Aug 21.
A popular model system for exploring the host-parasite relationship of gastrointestinal nematodes is commonly known as Heligmosomoides polygyrus bakeri. Recently, this parasite was raised to full species level as H. bakeri, to distinguish it from a close relative, H. polygyrus sensu stricto, the dominant intestinal nematode of wood mice in Western Europe, which is unable to infect laboratory mice (Mus sp.) without the aid of powerful immunosuppressants. Herein, the argument is presented that it is necessary to rename this parasite, and that H. bakeri is the correct name for the species used widely throughout the world as a laboratory research model. Supporting this claim, key evidence is presented demonstrating that H. bakeri and H. polygyrus are two quite distinct species.
一种常用于探索胃肠道线虫的宿主-寄生虫关系的流行模式系统通常被称为 Heligmosomoides polygyrus bakeri。最近，这种寄生虫被提升到了完整的物种水平，即 H. bakeri，以将其与近亲 Heligmosomoides polygyrus sensu stricto 区分开来，后者是西欧木鼠的主要肠道线虫，在没有强大的免疫抑制剂的帮助下，无法感染实验室小鼠（Mus sp.）。在此，提出论点认为有必要重新命名这种寄生虫，并且 H. bakeri 是作为实验室研究模型在世界范围内广泛使用的物种的正确名称。支持这一说法，提出了关键证据，表明 H. bakeri 和 H. polygyrus 是两个截然不同的物种。
