Radiology Department, AP-HP, Tenon Hospital, 4 Rue de la Chine, Paris 75020, France.
AJR Am J Roentgenol. 2010 Sep;195(3):772-8. doi: 10.2214/AJR.09.4161.
The aim of this study was to evaluate the ability of MDCT angiography to modify early results in patients undergoing endovascular embolization for hemoptysis.
A comparative study was performed of two consecutive cohorts with 200 patients each who were treated by endovascular embolization for severe hemoptysis; one cohort underwent MDCT angiography and the other did not, but patients underwent further exploration with global aortography. We compared the two groups for patients' age and sex and for the volume, cause, and mechanisms of hemoptysis. Evaluation included the number of sessions needed to control the hemoptysis, the primary failure of bronchial artery embolization, the recurrence of hemoptysis, pulmonary artery vasoocclusion, urgent surgical resection, and death by massive hemoptysis during hospitalization. Failure was defined as the absence of embolization during the first session. Recurrence was defined as rebleeding despite technically successful bronchial artery embolization.
Differences between the groups were statistically significant for patient age (p < 0.05), endovascular treatment failure among patients older than 70 years (p < 0.05), pulmonary artery vasoocclusion in comparison with diagnostic pulmonary artery angiography (p < 0.0001), and urgent surgical resection (p = 0.034).
The impact of MDCT angiography was significant in reducing the rate of vascular catheterization failure in patients older than 70 years, increasing the number of pulmonary artery vasoocclusions, and reducing the number of urgent surgical resection.
本研究旨在评估 MDCT 血管造影术在血管内栓塞治疗咯血患者中的早期疗效。
对 200 例因严重咯血而行血管内栓塞治疗的患者进行了连续两组的对比研究;一组行 MDCT 血管造影术,另一组未行 MDCT 血管造影术,但行全主动脉造影进一步探查。我们比较了两组患者的年龄和性别以及咯血的量、原因和机制。评估包括控制咯血所需的治疗次数、支气管动脉栓塞术的初次失败、咯血复发、肺动脉血管闭塞、紧急手术切除和住院期间因大咯血死亡。失败定义为第一次治疗时未栓塞。复发定义为尽管支气管动脉栓塞术技术成功,但仍再次出血。
两组患者的年龄(p < 0.05)、70 岁以上患者的血管内治疗失败(p < 0.05)、与诊断性肺动脉血管造影相比肺动脉血管闭塞(p < 0.0001)和紧急手术切除(p = 0.034)差异有统计学意义。
MDCT 血管造影术可显著降低 70 岁以上患者血管内治疗失败率,增加肺动脉血管闭塞的数量,减少紧急手术切除的数量。