Ittrich H, Klose H, Adam G
Diagnostic and Interventional Radiology Department and Clinic, Center for Radiology and Endoscopy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Department of Internal Medicine II and Clinic - Section Pneumology, Center for Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rofo. 2015 Apr;187(4):248-59. doi: 10.1055/s-0034-1385457. Epub 2014 Nov 5.
Hemoptysis can be a life-threatening pulmonary emergency with high mortality, is symptomatic of an underlying severe pulmonary disease and requires immediate diagnosis and treatment. Diagnostically, bronchoscopy, conventional chest x-ray and contrast-enhanced multislice computed tomography (MSCT) with CT angiography (CTA) provide information regarding the underlying pulmonary disease, bleeding site, the vascular anatomy of the bronchial arteries (BA) and extrabronchial branches, as well a basis for planning of endovascular intervention. Therapeutically, bronchial artery embolization (BAE) is a safe and effective technique in the hands of an experienced interventionist with profound knowledge of the BA anatomy and possible pitfalls as well as experience with first-line therapy of recurrent and massive hemoptysis or as an intervention prior to elective surgery. Recurrent episodes of hemoptysis are not uncommon and require a prompt repeat BAE after exclusion of extrabronchial systemic and pulmonary artery bleeding sources. This review article should give an overview of the history, anatomical and pathophysiological basics and the clinical context of hemoptysis and diagnosis, as well as a survey of management, treatment and results of BAE.
Hemoptyses are life threatening and require urgent diagnostic and therapy. Chest x-ray, bronchoscopy, and contrast-enhanced MSCT with CTA should be carried out before therapeutic bronchial artery embolization (BAE). BAE for the treatment of massive and recurrent hemoptysis is safe and effective. False embolization in spinal branches of BA are the most serious complication of a BAE. Repeatedly BAE refractory cases should undergo elective surgery.
咯血可能是一种危及生命的肺部急症,死亡率高,是潜在严重肺部疾病的症状,需要立即诊断和治疗。在诊断方面,支气管镜检查、传统胸部X线检查以及带有CT血管造影(CTA)的对比增强多层螺旋计算机断层扫描(MSCT)可提供有关潜在肺部疾病、出血部位、支气管动脉(BA)和支气管外分支的血管解剖结构的信息,也为血管内介入治疗的规划提供依据。在治疗方面,支气管动脉栓塞术(BAE)在经验丰富的介入医生手中是一种安全有效的技术,这些医生对BA解剖结构和可能的陷阱有深入了解,并且有治疗复发性和大量咯血的一线治疗经验或作为择期手术前的干预措施。咯血反复发作并不少见,在排除支气管外体循环和肺动脉出血源后,需要迅速重复进行BAE。这篇综述文章应概述咯血的历史、解剖和病理生理基础以及临床背景和诊断,以及BAE的管理、治疗和结果的调查。
咯血危及生命,需要紧急诊断和治疗。在进行治疗性支气管动脉栓塞术(BAE)之前,应进行胸部X线检查、支气管镜检查以及带有CTA的对比增强MSCT。BAE治疗大量和复发性咯血是安全有效的。BA脊髓分支的误栓塞是BAE最严重的并发症。反复进行BAE仍难治的病例应接受择期手术。