Kaufhold A, Krug E, Lütticken R, Knoop U, Bläker F
Institut für Medizinische Mikrobiologie, Rheinisch-Westfälischen Technischen Hochschule Aachen.
Monatsschr Kinderheilkd. 1991 Apr;139(4):208-13.
Four commercially prepared test reagent kits for the rapid screening of throat swabs for group A streptococci were examined in comparison to bacteriological cultures of 963 double throat swabs. The sensitivities of the test systems were 86.7% (Abbott Test Pack Strep A), 81.8% (Hybritech Tandem Icon Strep A), 79.6% (Pharmacia Phadirect Strep A), and 72.6% (Wellcome Reveal Colour Strep A) respectively. The specificity of the four tests was above 90%. Marked variations between different test reagent batches could be observed. The two tests based on the enzyme immunoassay principle proved to be superior to the agglutination tests investigated with respect to sensitivity and reading accuracy. Our results are evaluated in the light of the published literature on these tests.
将963份双侧咽拭子的细菌培养结果与4种用于快速筛查A群链球菌的市售检测试剂进行了比较。检测系统的灵敏度分别为86.7%（雅培A群链球菌检测试剂盒）、81.8%（海普瑞康串联免疫分析A群链球菌检测试剂盒）、79.6%（法玛西亚快速检测A群链球菌试剂盒）和72.6%（威康显色A群链球菌检测试剂盒）。这4种检测的特异性均高于90%。不同检测试剂批次之间存在明显差异。基于酶免疫分析原理的两种检测方法在灵敏度和读数准确性方面优于所研究的凝集试验。我们根据已发表的关于这些检测的文献对结果进行了评估。
