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恶性外生性骨疣:慢性皮肤溃疡处理不当的后果。

Marjolin's ulcer: Sequelae of mismanaged chronic cutaneous ulcers.

机构信息

Department of Surgery, University of Calabar Teaching Hospital, Nigeria.

出版信息

Adv Skin Wound Care. 2010 Sep;23(9):414-6. doi: 10.1097/01.ASW.0000383211.18782.2a.

Abstract

OBJECTIVE

This study was to evaluate the current pattern and risk factors of Marjolin's ulcer in the authors' setting.

SETTINGS AND PARTICIPANTS

Twenty-one patients with histological diagnosis of skin malignancy at the University of Calabar Teaching Hospital, Calabar, Nigeria.

METHODS

Presented are patients with histologic diagnosis of Marjolin's seen in the University of Calabar Teaching Hospital, Calabar, Nigeria from January 2007 through December 2007.

RESULTS

Five patients (3 men and 2 women) with Marjolin's ulcer whose ages ranged from 32 to 70 years (mean 46.6 years) accounted for 45.5% of squamous cell carcinoma. All the patients suffered traumatic injuries (4 lower limb injuries from road traffic accidents and 1 puncture wound of the upper limb) and the latency was 21.4 years.

CONCLUSIONS

Chronic trauma-induced limb ulceration is the leading risk factor for Marjolin's ulcer. Health education, early detection, and proper management of chronic wounds would improve outcome.

摘要

目的

本研究旨在评估作者所在环境中马约林溃疡的当前模式和危险因素。

地点和参与者

尼日利亚卡拉巴尔大学教学医院的 21 名患有皮肤恶性肿瘤组织学诊断的患者。

方法

呈现的是 2007 年 1 月至 2007 年 12 月在尼日利亚卡拉巴尔大学教学医院就诊的患有马约林溃疡的组织学诊断的患者。

结果

5 例(3 男 2 女)马约林溃疡患者年龄 32 至 70 岁(平均 46.6 岁),占鳞状细胞癌的 45.5%。所有患者均遭受创伤性损伤(4 例下肢损伤来自道路交通意外,1 例上肢刺伤),潜伏期为 21.4 年。

结论

慢性创伤性肢体溃疡是马约林溃疡的主要危险因素。健康教育、早期发现和适当处理慢性伤口将改善预后。

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