Molecular characterization of non-histone chromatin proteins from experimental tumours. - Suppr | 超能文献

Molecular characterization of non-histone chromatin proteins from experimental tumours.

作者信息

Kiliańska Z, Krajewska W M, Lipińska A, Marszałek M, Gaczyński M, Kłyszejko-Stefanowicz L

机构信息

Department of Cytobiochemistry, Institute of Biochemistry, University of Lódź, Poland.

出版信息

Acta Biochim Pol. 1990;37(2):267-75.

Abstract

Using two-dimensional (2-D) electrophoresis, two non-histone chromatin protein fractions (NHCP1 and NHCP2) from three animal tumours (Kirkman-Robbins hepatoma, Morris hepatoma 7777 and Ehrlich ascites cells) and normal hamster liver were analyzed. Apart from many common components several tissue specific polypeptides of the NHCP1 and NHCP2 fractions were detected. It was found that some spots present in electropherograms of non-histone proteins of tumour cells (M X 10(-3)/pI): 17-24/4.9-6.5 (NHCP1 and NHCP2); 34-41/4.9-6.0 (HCP1 and NHCP2); 44-46/5.3-7.5 (HCP2); 46-49/5.0-7.5 (NHCP1); 49/5.9-7.5 (NHCP2) and 102-134/5.6-7.0 (NHCP1) were absent from normal liver.

摘要

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