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一种用于治疗寻常痤疮的6%过氧化苯甲酰泡沫布式洁面产品:美学特性、患者偏好考量以及对治疗依从性的影响

A 6% benzoyl peroxide foaming cloth cleanser used in the treatment of acne vulgaris: aesthetic characteristics, patient preference considerations, and impact on compliance with treatment.

作者信息

Del Rosso James Q

机构信息

Valley Hospital Medical Center, Las Vegas, Nevada.

出版信息

J Clin Aesthet Dermatol. 2009 Jul;2(7):26-9.

PMID:20729967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2924139/
Abstract

OBJECTIVE

The study was conducted to evaluate the product attributes of a new benzoyl peroxide-containing foaming cloth cleanser and to compare the overall patient satisfaction of this product with two currently available benzoyl peroxide acne products (6% benzoyl peroxide cleanser and 4% benzoyl peroxide wash).

DESIGN

This was a randomized, single-blind study.

SETTING

Two clinical trial sites.

PARTICIPANTS

Male and female subjects (N=193) aged 17 to 30 years with a history of acne vulgaris were enrolled.

MEASURES

Subjects initially cleansed their face with the benzoyl peroxide foaming cloth and then completed a product-attribute survey. Following an interval of five minutes or more, subjects cleansed their face again using one of two randomly assigned comparator benzoyl peroxide-containing cleansing products and then completed a comparative survey. Survey results were tabulated and a top-two box analysis was performed.

RESULTS

Following the use of the benzoyl peroxide-containing foaming cloth, 94 percent of the product-attribute responses were positive (p</=0.05). With respect to convenience, usability, and cosmetic elegance, the majority of subjects indicated a preference for the benzoyl peroxide foaming cloth compared to the 6% benzoyl peroxide cleanser and 4% benzoyl peroxide wash (for each, p</=0.05). There were no reports of adverse events.

CONCLUSION

These attributes supporting preference for the benzoyl peroxide foaming cloth cleanser may improve patient satisfaction with topical acne treatment resulting in improved patient compliance. (J Clin Aesthetic Dermatol. 2009;2(7):26-29.).

摘要

目的

本研究旨在评估一种新型含过氧化苯甲酰的泡沫洁面巾的产品特性,并将该产品与两种市售的过氧化苯甲酰痤疮产品(6%过氧化苯甲酰洁面乳和4%过氧化苯甲酰洗液)的总体患者满意度进行比较。

设计

这是一项随机单盲研究。

地点

两个临床试验地点。

参与者

招募了17至30岁有寻常痤疮病史的男性和女性受试者(N = 193)。

测量方法

受试者先用含过氧化苯甲酰的泡沫洁面巾洗脸,然后完成一份产品特性调查问卷。间隔五分钟或更长时间后,受试者再使用两种随机分配的含过氧化苯甲酰的对照清洁产品之一洗脸,然后完成一份比较调查问卷。对调查结果进行列表统计,并进行前两档分析。

结果

使用含过氧化苯甲酰的泡沫洁面巾后,94%的产品特性反馈为积极(p≤0.05)。在便利性、易用性和外观美观方面,与6%过氧化苯甲酰洁面乳和4%过氧化苯甲酰洗液相比,大多数受试者表示更喜欢含过氧化苯甲酰的泡沫洁面巾(每种情况,p≤0.05)。没有不良事件报告。

结论

这些支持对含过氧化苯甲酰泡沫洁面巾偏好的特性可能会提高患者对局部痤疮治疗的满意度,从而提高患者的依从性。(《临床美容皮肤科杂志》。2009年;2(7):26 - 29。)

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本文引用的文献

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Benzoyl peroxide cleansers for the treatment of acne vulgaris: status report on available data.用于治疗寻常痤疮的过氧化苯甲酰洁面产品:现有数据的状况报告
Cutis. 2008 Nov;82(5):336-42.
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Emerging topical antimicrobial options for mild-to-moderate acne: a review of the clinical evidence.轻度至中度痤疮的新型局部抗菌治疗选择:临床证据综述
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Current concepts in acne management.痤疮管理的当前概念。
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Psychological problems in the acne patient.痤疮患者的心理问题。
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Tricks for improving compliance with acne therapy.提高痤疮治疗依从性的技巧。
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Conjoint analysis: a novel, rigorous tool for determining patient preferences for topical antibiotic treatment for acne. A randomised controlled trial.联合分析:一种用于确定患者对痤疮局部抗生素治疗偏好的新颖、严谨的工具。一项随机对照试验。
Br J Dermatol. 2006 Mar;154(3):524-32. doi: 10.1111/j.1365-2133.2005.07047.x.
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Novel drug delivery systems: potential in improving topical delivery of antiacne agents.新型药物递送系统:改善抗痤疮药物局部递送的潜力。
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Current concepts in the treatment of acne: report from a clinical roundtable.痤疮治疗的当前理念:临床圆桌会议报告
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