Pourzand Ali, Fakhri Bassir A, Azhough Ramin, Hassanzadeh Mohammad Ali, Hashemzadeh Shahryar, Bayat Amrollah M
Department of General Surgery, Tabriz University of Medical Sciences, Tabriz, East Azarbaijan Province, Iran.
Vasc Health Risk Manag. 2010 Aug 9;6:613-8. doi: 10.2147/vhrm.s11733.
The purpose of this study is to report the clinical and functional outcomes of patients, treated between 2004 and 2009, with high-risk popliteal vascular injuries due to compound fractures about the knee.
A retrospective analysis was conducted of prospectively collected data from Tabriz Medical Trauma Center. Our aim was to perform surgical revascularization as soon as the arterial injury was recognized. The mechanism of injury was blunt in the entire cohort of patients, and all of them had bone fractures about the knee. The treatment of arterial injury included vein graft interposition in 39 (63%), primary anastomosis in 20 (32.3%), and lateral repair in 3 (4.8%) patients. The patients were divided into 2 study groups: limb salvage group (group 1) and amputation group (group 2). Subgroup analysis consisted of univariate analysis comparing the 2 groups and multivariate analysis examining the factors associated negatively and positively with the primary endpoint, limb salvage.
In the entire cohort of patients, 60 patients (97%) were male and 2 were female (3%); the mean age was 34.1 years (16-49 years). The overall amputation rate in this study was 37.1% (23 amputations). Significant (P < 0.05) independent factors associated negatively with limb salvage were combined tibia and fibula fracture, concomitant artery and vein injury, ligation of venous injury, and lack of backflow after Fogarty catheter thrombectomy, while repair of popliteal artery and vein injury, when present, was associated with improved early limb salvage. For 40 patients, we adopt a liberal attitude toward open 4-compartment fasciotomy through both medially and laterally placed incisions.
Expeditious recognition of vascular injury, transport to repair, and repair of associated venous injury when possible are necessary to optimize limb salvage. The importance of a high level of suspicion and low threshold for timely amputation has been emphasized when limb salvage was deemed impossible to prevent life-threatening complication. Delays in surgery, extensive soft tissue defect, compound tibia-fibula fracture, and other factors are associated with high amputation rate following popliteal artery injury.
本研究旨在报告2004年至2009年间因膝关节周围复合骨折导致高危腘血管损伤患者的临床和功能结局。
对大不里士医学创伤中心前瞻性收集的数据进行回顾性分析。我们的目标是一旦识别出动脉损伤,尽快进行手术血运重建。所有患者的损伤机制均为钝性损伤,且均有膝关节周围骨折。动脉损伤的治疗包括39例(63%)患者采用静脉移植搭桥、20例(32.3%)患者进行一期吻合、3例(4.8%)患者进行外侧修复。患者被分为2个研究组:保肢组(第1组)和截肢组(第2组)。亚组分析包括比较两组的单因素分析以及检验与主要终点(保肢)呈负相关和正相关因素的多因素分析。
在整个患者队列中,60例(97%)为男性,2例(3%)为女性;平均年龄为34.1岁(16 - 49岁)。本研究的总体截肢率为37.1%(23例截肢)。与保肢呈负相关的显著(P < 0.05)独立因素包括胫腓骨联合骨折、动脉和静脉合并损伤、静脉损伤结扎以及Fogarty导管取栓术后无回血,而腘动脉和静脉损伤(若存在)的修复与早期保肢改善相关。对于40例患者,我们对通过内侧和外侧切口进行的开放性四室筋膜切开术持宽松态度。
迅速识别血管损伤、转运至进行修复以及尽可能修复相关静脉损伤对于优化保肢至关重要。当认为保肢不可能以预防危及生命的并发症时,强调了高度怀疑和低截肢阈值的重要性。手术延迟、广泛的软组织缺损、胫腓骨复合骨折以及其他因素与腘动脉损伤后的高截肢率相关。