Department of Internal Medicine, Nerima General Hospital, Asahigaoka, Nerima-ku, Tokyo, Japan.
Ups J Med Sci. 2010 Nov;115(4):282-6. doi: 10.3109/03009734.2010.486908. Epub 2010 Aug 23.
A 56-year-old woman with Graves' disease presented with the complaints of diarrhea and palpitations. Physical examination and laboratory data revealed hypothermia and signs of mild hyperthyroidism, heart failure, hepatic dysfunction with jaundice, hypoglycemia, and lactic acidosis. The patient was diagnosed as having developed the complication of thyroid storm in the absence of marked elevation of the thyroid hormone levels, because of the potential hepatic and cardiac dysfunctions caused by heavy alcohol drinking. A year later, after successful treatment, the patient remains well without any clinical evidence of heart failure or hepatic dysfunction. Thyroid storm associated with lactic acidosis and hypothermia is a serious condition and has rarely been reported. Prompt treatment is essential even if the serum thyroid hormone levels are not markedly elevated. We present a report about this patient, as her life could eventually be saved.
一位 56 岁的 Graves 病女性患者因腹泻和心悸就诊。体格检查和实验室数据显示体温过低和轻度甲状腺功能亢进、心力衰竭、肝损伤伴黄疸、低血糖和乳酸性酸中毒的迹象。由于重度饮酒导致的潜在肝和心脏功能障碍,尽管甲状腺激素水平没有明显升高,该患者仍被诊断为发生了甲状腺危象并发症。一年后,经过成功治疗,患者情况良好,没有心力衰竭或肝损伤的临床证据。甲状腺危象伴乳酸性酸中毒和体温过低是一种严重的情况,很少有报道。即使血清甲状腺激素水平没有明显升高,也需要及时治疗。我们报告了这位患者的情况,因为她的生命最终得以挽救。