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甲状腺危象伴多器官功能衰竭。

Thyroid storm with multiorgan failure.

机构信息

Division of Respiratory and Critical Care Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.

出版信息

Thyroid. 2010 Mar;20(3):333-6. doi: 10.1089/thy.2009.0181.

DOI:10.1089/thy.2009.0181
PMID:20146655
Abstract

BACKGROUND

Thyroid storm is a rare and potentially fatal condition. Various unusual presentations in patients with thyroid storm have been described but multiorgan dysfunction is uncommonly seen.

SUMMARY

We describe a 35-year-old patient with a history of Graves' disease who was diagnosed with thyroid storm at 2 weeks postpartum. This was complicated by acute liver failure, acute kidney injury, severe lactic acidosis, disseminated intravascular coagulation, and heart failure with acute pulmonary edema. The multiorgan dysfunction was reversed by prompt institution of antithyroid drugs and supportive management in the intensive care unit.

CONCLUSION

Thyroid storm is a medical emergency. One of the challenges lies in recognizing its varied presentations. Early diagnosis and appropriate treatment is important to prevent the catastrophic outcomes associated with this condition.

摘要

背景

甲状腺危象是一种罕见且可能致命的疾病。甲状腺危象患者有各种不寻常的表现,但多器官功能障碍并不常见。

摘要

我们描述了一位 35 岁有格雷夫斯病病史的患者,她在产后 2 周时被诊断为甲状腺危象。该患者还并发了急性肝衰竭、急性肾损伤、严重乳酸性酸中毒、弥漫性血管内凝血和心力衰竭伴急性肺水肿。在重症监护病房,通过迅速使用抗甲状腺药物和支持性治疗,多器官功能障碍得到逆转。

结论

甲状腺危象是一种急症。其中一个挑战在于认识其各种表现。早期诊断和适当的治疗对于预防与这种情况相关的灾难性结局非常重要。

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