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双相直流电转复剂量治疗儿科房性心律失常。

Biphasic DC shock cardioverting doses for paediatric atrial dysrhythmias.

机构信息

Intensive Care Unit, Royal Children's Hospital, Flemington Road, Parkville, Melbourne, Victoria 3052, Australia.

出版信息

Resuscitation. 2010 Sep;81(9):1101-4. doi: 10.1016/j.resuscitation.2010.04.028. Epub 2010 Jun 17.

Abstract

OBJECTIVE

To determine cardioversion doses of biphasic DC shock for paediatric atrial dysrhythmias.

DESIGN

Prospective recording of energy, pre-shock and post-shock rhythms.

SETTING

Paediatric hospital.

PATIENTS

Shockable atrial dysrhythmias.

MAIN RESULTS

Forty episodes of atrial dysrhythmias among 25 children (mean age 6.8+/-7.1 years, mean weight 28.2+/-28.5 kg) were treated with external shock. The first shock converted the dysrhythmia to sinus rhythm in 25 episodes. Cardioversion occurred in 2 of 8 (25%) episodes with a dose of <0.5 J/kg, 14 of 16 (88%) with a dose of 0.5-1.0 J/kg and 9 of 16 (56%) with a dose of >1.0 J/kg (p=0.01, Fisher's exact test). Ten of 15 initially non-responsive episodes were cardioverted with additional shocks at 1.1+/-0.6 J/kg (range 0.5-2.1 J/kg). Of the remaining 5 unresponsive episodes, 2 of ventricular fibrillation (induced by unsynchronized shock) were successfully defibrillated, and 3 were managed with cardiopulmonary bypass. Among 11 additional children (mean age 4.3+/-6.8 years, mean weight 18.1+/-22.0 kg), 18 episodes of atrial dysrhythmias were treated with internal shock which successfully cardioverted all episodes with one or more shocks at 0.4+/-0.2 J/kg.

CONCLUSIONS

In rounded doses, recommended initial external cardioversion doses are 0.5-1.0 J/kg and subsequently up to 2 J/kg, internal cardioversion doses are 0.5 J/kg.

摘要

目的

确定双相直流电击用于儿科房性心律失常的转复剂量。

设计

对能量、电击前和电击后节律进行前瞻性记录。

设置

儿科医院。

患者

可电击的房性心律失常。

主要结果

25 名儿童(平均年龄 6.8+/-7.1 岁,平均体重 28.2+/-28.5kg)中有 40 例房性心律失常发作接受了外部电击治疗。在 25 例中,第 1 次电击使心律失常转为窦性心律。在剂量<0.5 J/kg 的 8 例中,2 例(25%)出现转复;在剂量为 0.5-1.0 J/kg 的 16 例中,14 例(88%)出现转复;在剂量>1.0 J/kg 的 16 例中,9 例(56%)出现转复(p=0.01,Fisher 确切检验)。15 例最初无反应的病例中有 10 例在 1.1+/-0.6 J/kg(0.5-2.1 J/kg 范围)时进行了额外电击转复。在其余 5 例无反应的病例中,2 例心室颤动(由非同步电击引起)被成功除颤,3 例采用心肺旁路治疗。在另外 11 名儿童(平均年龄 4.3+/-6.8 岁,平均体重 18.1+/-22.0kg)中,18 例房性心律失常发作采用内源性电击治疗,所有患者在 0.4+/-0.2 J/kg 时接受一次或多次电击均成功转复。

结论

在整数剂量下,推荐的初始外部转复剂量为 0.5-1.0 J/kg,随后可达 2 J/kg;内源性转复剂量为 0.5 J/kg。

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