Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Curr Opin Organ Transplant. 2010 Oct;15(5):582-7. doi: 10.1097/MOT.0b013e32833e3e6e.
Anastomotic airway complications continue to plague recovery after lung transplantation and serve as a major source of morbidity and mortality. Prevalence has surprisingly remained relatively constant over the last decade, despite improvement in overall transplant survival.
Anastomotic airway complications occur in about one-fifth of patients following lung transplantation and are formidable and persistent problems. Technical issues associated with complications are difficult to define, but may include telescoping anastomoses and donor-recipient size mismatch. Endobronchial therapy of complications has reduced early mortality, but may not impact the late deleterious consequences of these complications. A therapeutic algorithm has been developed to assist clinicians.
Despite increasing experience, anastomotic airway complications remain problematic. Continued investigation into this process appears warranted, given the impact and prevalence. Very few risk factors currently appear modifiable, however.
吻合口气道并发症在肺移植后持续困扰着患者的恢复，是发病率和死亡率的主要来源。尽管整体移植存活率有所提高，但令人惊讶的是，在过去十年中，吻合口气道并发症的患病率仍然相对稳定。
吻合口气道并发症在肺移植后约五分之一的患者中发生，是严重且持久的问题。与并发症相关的技术问题难以定义，但可能包括套叠吻合和供体-受者大小不匹配。支气管内治疗并发症降低了早期死亡率，但可能不会影响这些并发症的晚期不良后果。已经制定了治疗算法来帮助临床医生。
尽管经验不断增加，但吻合口气道并发症仍然是个问题。鉴于其影响和普遍性，进一步研究这一过程似乎是必要的。然而，目前似乎很少有风险因素是可以改变的。
