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移位的自膨式金属气管支气管支架的重新定位:成功操作的预测因素及其对生存的影响。

Repositioning of migrated self-expanding metallic tracheobronchial stent: predictors of a successful maneuver and its impact on survival.

作者信息

Biswas Abhishek, Jantz Michael A, Fernandez-Bussy Sebastian, Flanagan Mindy, Mehta Hiren J

机构信息

Parkview Regional Medical Center, Fort Wayne, Indiana, USA.

University of Florida, Gainesville, Florida, USA.

出版信息

J Thorac Dis. 2020 May;12(5):1866-1876. doi: 10.21037/jtd-20-608.

Abstract

BACKGROUND

Endobronchial stents that are used to treat airway obstruction may migrate over time. These stents can be repositioned. However, not much has been reported about this technique. We retrospectively reviewed our experience with self-expanding metallic stents (SEMS) and attempted to determine-(I) factors related to successful stent repositioning; (II) determine its impact on survival.

METHODS

Demographic, medical history, and stent-related procedure factors were extracted from the electronic health record. Primary outcomes were bronchial stent repositioning success and survival (days until death). As validation of successful repositioning, the durations of successful and failed repositioning procedures were compared using an independent -test.

RESULTS

Seventy-six patients underwent stent repositioning, of which, 55.3% (n=42) were successfully repositioned. The probability of success in repositioning procedures was accounted for by patient sex, stent location, and stent diameter. Females were more likely to have a successful repositioning compared to males. Stent repositioning in the LMS was more likely to be successful and stents larger in diameter tended to increase the likelihood of successful repositioning. Long-term survival was higher for those who had a successful procedure. Stent location and disease subgroups predicted average length of survival.

CONCLUSIONS

Repositioning of migrated stents can be successfully performed regardless of the reasons for initial placement, duration of stenting and degree of original obstruction. Larger stents are easier to reposition and so were stents in the left main stem (LMS) airway. A successful stent repositioning maneuver improved long-term survival although did not have any impact survival in the immediate post-procedural period.

摘要

背景

用于治疗气道阻塞的支气管内支架可能会随着时间推移而移位。这些支架可以重新定位。然而,关于这项技术的报道并不多。我们回顾性分析了我们使用自膨式金属支架(SEMS)的经验,并试图确定:(I)与支架成功重新定位相关的因素;(II)其对生存的影响。

方法

从电子健康记录中提取人口统计学、病史和支架相关手术因素。主要结局为支气管支架重新定位成功和生存情况(至死亡的天数)。作为对成功重新定位的验证,使用独立样本t检验比较成功和失败重新定位手术的持续时间。

结果

76例患者接受了支架重新定位,其中55.3%(n = 42)成功重新定位。重新定位手术成功的概率由患者性别、支架位置和支架直径决定。女性比男性更有可能成功重新定位。左主支气管(LMS)的支架重新定位更有可能成功,直径较大的支架往往会增加成功重新定位的可能性。手术成功的患者长期生存率更高。支架位置和疾病亚组可预测平均生存时间。

结论

无论初始放置的原因、支架置入时间和原始阻塞程度如何,移位支架的重新定位均可成功进行。较大的支架更容易重新定位,左主支气管(LMS)气道内的支架也是如此。成功的支架重新定位操作可提高长期生存率,尽管在术后即刻对生存没有任何影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a34d/7330314/10298615de30/jtd-12-05-1866-f1.jpg

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本文引用的文献

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Ann Cardiothorac Surg. 2018 Mar;7(2):273-283. doi: 10.21037/acs.2018.03.08.
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The use of self-expandable metallic stents in the airways in the adult population.成人气道中自膨式金属支架的应用。
Expert Rev Respir Med. 2014 Apr;8(2):179-90. doi: 10.1586/17476348.2014.880055. Epub 2014 Jan 22.
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Anastomotic airway complications after lung transplantation.肺移植术后吻合口气道并发症。
Curr Opin Organ Transplant. 2010 Oct;15(5):582-7. doi: 10.1097/MOT.0b013e32833e3e6e.
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Airway stents.气道支架。
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