Pembe A B, Abeid M S
Department of Obstetrics and Gynaecology, Muhimbili University of Health and Allied Sciences, P.O. Box 65117, Dar es Salaam, Tanzania.
Tanzan J Health Res. 2009 Oct;11(4):175-80. doi: 10.4314/thrb.v11i4.50172.
The aim of this study was to determine prevalence of polycystic ovaries (PCO) and associated clinical and biochemical features among women with infertility attending gynaecological outpatient department (GOPD) at Muhimbili National Hospital (MNH) in Dar es Salaam, Tanzania. All women with infertility attending the GOPD from 11th September 2006 to 15th February 2007 were recruited to the study. Information on socio-demographic, obstetric and menstrual characteristics was collected. Anthropometric measurement, clinical examination of acne and hirsutism, vaginal ultrasonography for PCO and biochemical analysis of luteinizing hormone (LH), follicle stimulating hormone (FSH) and testosterone were performed. All 102 women who attended the GOPD during the study period due to infertility were recruited. Two women were excluded after diagnosis of pregnancy made by hormonal assay and ultrasonography thus remaining with 100 women for analysis. Oligomenorrhoea and acne were significantly higher in a group of women with PCO than among women with normal ovaries. The mean hirsutism score though was not significant, was higher in women with PCO than in women with normal ovaries (5.1 +/- 2.7 vs. 4 +/- 2.4, P < 0.057). Using the Rotterdam criteria 32 (32%) women were diagnosed to have polycystic ovary syndrome (PCOS). Among these women 25 (78.1%) had PCO, 24 (75%) had signs of oligoanovulation, and 18 (56.3%) had hirsutism. Among 68 women with no PCOS, 7 (10.3%) had polycystic ovaries, 15 (22.1%) had signs of oligoanovulation and 6 (8.8%) had hirsutism. In conclusion, polycystic ovaries are common among women with infertility, however are not necessarily associated with polycystic ovary syndrome. Doctors should investigate their clients for PCOS and offer appropriate treatment.
本研究旨在确定坦桑尼亚达累斯萨拉姆市穆希姆比利国家医院（MNH）妇科门诊（GOPD）就诊的不孕女性中多囊卵巢（PCO）的患病率以及相关的临床和生化特征。2006年9月11日至2007年2月15日期间在GOPD就诊的所有不孕女性均被纳入本研究。收集了社会人口统计学、产科和月经特征方面的信息。进行了人体测量、痤疮和多毛症的临床检查、用于诊断PCO的阴道超声检查以及促黄体生成素（LH）、促卵泡生成素（FSH）和睾酮的生化分析。在研究期间因不孕而到GOPD就诊的102名女性均被纳入。两名女性经激素检测和超声检查诊断为妊娠后被排除，因此剩余100名女性进行分析。PCO组女性的月经过少和痤疮发生率显著高于正常卵巢女性。尽管多毛症平均评分无显著差异，但PCO女性的多毛症评分高于正常卵巢女性（5.1±2.7 vs. 4±2.4，P<0.057）。根据鹿特丹标准，32名（32%）女性被诊断为多囊卵巢综合征（PCOS）。在这些女性中，25名（78.1%）有PCO，24名（75%）有排卵少的迹象，18名（56.3%）有多毛症。在68名无PCOS的女性中，7名（10.3%）有PCO，15名（22.1%）有排卵少的迹象，6名（8.8%）有多毛症。总之，多囊卵巢在不孕女性中很常见，但不一定与多囊卵巢综合征相关。医生应检查患者是否患有PCOS并提供适当治疗。
