Adams J, Polson D W, Franks S
Br Med J (Clin Res Ed). 1986 Aug 9;293(6543):355-9. doi: 10.1136/bmj.293.6543.355.
Polycystic ovaries were defined with ultrasound imaging in a series of 173 women who presented to a gynaecological endocrine clinic with anovulation or hirsutism. Polycystic ovaries were found in 26% of women with amenorrhoea, 87% with oligomenorrhoea, and 92% with idiopathic hirsutism--that is, hirsutism but with regular menstrual cycles. Fewer than half the anovulatory patients with polycystic ovaries were hirsute, but in 93% of cases there was at least one endocrine abnormality to support the diagnosis of polycystic ovaries--that is, raised serum concentrations of luteinising hormone, raised luteinising hormone: follicle stimulating hormone ratio, or raised serum concentrations of testosterone or androstenedione. This study shows that polycystic ovaries, as defined by pelvic ultrasound, are very common in anovulatory women (57% of cases) and are not necessarily associated with hirsutism or a raised serum luteinising hormone concentration. Most women with hirsutism and regular menses have polycystic ovaries so that the term "idiopathic" hirsutism no longer seems appropriate.
在一家妇科内分泌诊所,对173名因无排卵或多毛症前来就诊的女性进行超声成像检查,以此来定义多囊卵巢。在闭经女性中,26%被发现有多囊卵巢;在月经过少女性中,87%有多囊卵巢;在特发性多毛症(即有毛发过多现象但月经周期正常)女性中,92%有多囊卵巢。多囊卵巢的无排卵患者中,不到一半有多毛症状,但在93%的病例中,至少有一项内分泌异常支持多囊卵巢的诊断,即血清促黄体生成素浓度升高、促黄体生成素与促卵泡激素比值升高,或血清睾酮或雄烯二酮浓度升高。这项研究表明,根据盆腔超声定义的多囊卵巢在无排卵女性中非常常见(占病例的57%),且不一定与多毛症或血清促黄体生成素浓度升高有关。大多数有毛发过多现象且月经周期正常的女性都有多囊卵巢,因此“特发性”多毛症这一术语似乎不再合适。