Barbakadze Vakhtang, Gogilashvili Lali, Amiranashvili Lela, Merlani Maia, Mulkijanyan Karen, Churadze Manana, Salgado Antonio, Chankvetadze Bezhan
I. Kutateladze Institute of Pharmacochemistry, 36 P. Sarajishvili str., 0159 Tbilisi, Georgia.
Nat Prod Commun. 2010 Jul;5(7):1091-5.
Elucidation of the main structural unit of a water-soluble, high-molecular weight preparation from the crude polysaccharides of Anchusa italica Retz. roots has been carried out. According to 13C NMR, 1H NMR and 2D heteronuclear 1H/13C HSQC spectral data, the main structural element of the high-molecular, water-soluble preparation was a regularly substituted polyoxyethylene chain, namely poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene]. Most carboxylic groups of this caffeic acid-derived polymer of A. italica are methylated.
对来自意大利牛舌草（Anchusa italica Retz.）根的粗多糖中一种水溶性高分子量制剂的主要结构单元进行了阐明。根据13C NMR、1H NMR和二维异核1H/13C HSQC光谱数据，该高分子水溶性制剂的主要结构元素是规则取代的聚氧乙烯链，即聚[氧-1-羧基-2-(3,4-二羟基苯基)乙烯]。这种源自意大利牛舌草咖啡酸的聚合物的大多数羧基被甲基化。
