Devesa S S, Blot W J, Fraumeni J F
Division of Cancer Etiology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
Epidemiology. 1990 Mar;1(2):116-21. doi: 10.1097/00001648-199003000-00006.
Temporal patterns in mortality from 1950 to 1984 in the United States for oral, esophageal, and laryngeal cancers show some similarities but differ markedly by sex and race. Cohort analyses reveal that among white women, rates for all three cancers declined among those born during the latter half of the 1800s, increased among those born between about 1895 and 1920, and decreased thereafter. Rates among nonwhite women generally follow the patterns among white women, with a lag of about five years. Among white men, except for declining oral cancer mortality among those born from the mid- to late 1800s, cohort-specific patterns are much less remarkable, whereas increases for oral, esophageal, and laryngeal cancers among nonwhite male cohorts born since 1900 have been steep and have not yet reversed direction as they have for whites. Gender and racial differences in tobacco and alcohol consumption as well as dietary factors are explored as explanations for these patterns.
1950年至1984年美国口腔癌、食管癌和喉癌死亡率的时间模式显示出一些相似之处，但在性别和种族方面存在显著差异。队列分析表明，在白人女性中，这三种癌症的发病率在19世纪后半叶出生的人群中有所下降，在大约1895年至1920年出生的人群中有所上升，此后又有所下降。非白人女性的发病率总体上遵循白人女性的模式，但有大约五年的滞后。在白人男性中，除了19世纪中叶至后期出生的人群口腔癌死亡率下降外，特定队列的模式不太明显，而自1900年以来出生的非白人男性队列中口腔癌、食管癌和喉癌的发病率急剧上升，尚未像白人那样逆转趋势。研究了烟草和酒精消费以及饮食因素方面的性别和种族差异，以解释这些模式。
