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球后型类肉瘤病全身免疫抑制治疗后视网膜结构的恢复。

Restoration of retinal architecture following systemic immunosuppression in birdshot chorioretinopathy.

机构信息

Department of Ophthalmology, Mount Sinai School of Medicine, New York, New York 10029, USA.

出版信息

Ocul Immunol Inflamm. 2010 Dec;18(6):470-1. doi: 10.3109/09273948.2010.506973. Epub 2010 Aug 25.

Abstract

PURPOSE

To describe restoration of retinal architecture following systemic immunosuppressive treatment in a patient with birdshot chorioretinopathy (BSCR).

DESIGN

Case report.

METHODS

A patient with BSCR and vitritis, reduced electroretinographic responses, and a constricted visual field was treated with prednisone and mycophenolate mofetil.

RESULTS

Spectral domain optical coherence tomography (SD-OCT) at baseline demonstrated a disruption of retinal architecture. After 4 months of treatment retinal architecture, as visualized on SD-OCT, was restored to normal.

CONCLUSIONS

Treatment of BSCR with systemic immunosuppression can result in restoration of disrupted retinal architecture. This structural improvement can be visualized and assessed using SD-OCT.

摘要

目的

描述一位患鸟枪弹样脉络膜视网膜炎(BSCR)患者在接受全身免疫抑制治疗后视网膜结构的恢复情况。

设计

病例报告。

方法

对一位患有 BSCR 和葡萄膜炎、光感受器电反应降低以及视野受限的患者,给予泼尼松和霉酚酸酯治疗。

结果

基线时的频域光学相干断层扫描(SD-OCT)显示视网膜结构中断。治疗 4 个月后,SD-OCT 显示视网膜结构恢复正常。

结论

全身免疫抑制治疗 BSCR 可导致破坏的视网膜结构恢复。这种结构的改善可以使用 SD-OCT 进行观察和评估。

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