Arthritis Res Ther. 2010;12(4):134. doi: 10.1186/ar3099. Epub 2010 Aug 13.
Predicting complications of diseases such as rheumatoid arthritis (RA) as well as the efficacy and toxicity of drugs used to treat the disease based on an understanding of genetic differences is leading to the development of highly individualized, personal medicine. The prevention of cardiovascular complications of RA has assumed greater importance as our ability to treat the underlying joint disease has improved and it may be possible to predict which patients with RA are at greatest risk of developing cardiovascular disease.
基于对遗传差异的理解,预测类风湿关节炎 (RA) 等疾病的并发症以及用于治疗该疾病的药物的疗效和毒性,正引领着高度个体化、个性化医学的发展。随着我们治疗潜在关节疾病能力的提高,RA 的心血管并发症的预防变得更为重要,而且有可能预测出哪些 RA 患者面临最大的心血管疾病风险。