University of Birmingham, Edgbaston, UK.
Appetite. 2010 Dec;55(3):718-21. doi: 10.1016/j.appet.2010.08.009. Epub 2010 Aug 22.
This short overview considers a prospect that claims to boost satiety are used to prescribe or sell materials to dieters that do not slow their daily rate of energy intake, thereby worsening their problems with body weight and even perhaps increasing the prevalence of obesity. Implying that a drug or a food contributes to weight control by providing extra satiety is a mistake in two ways. First, the notion of a hormone analogue or a food constituent having a specifiable satiating power is scientifically incoherent. Secondly, a slimming satiety is a particular pattern of eating and drinking, in which substances have no fixed roles. Such a dietary custom has to be shown to produce a larger step decrease in weight with the medication or food product than without it. Suppression of food intake at a usual time for eating does not imply reduction in the eater's total intake of energy in a calendar period and hence lower weight while the material is still used within that eating pattern. It is the maintained pattern of behaviour that slims and prevents regain, not a satiety-augmenting substance. Regulators should not allow incomprehension of the basic science of energy balance to be exploited by advocacy of a food or medication for "satiety" believed by consumers to be a means of avoiding unhealthy fatness.
这篇简短的综述考虑了一种观点,即声称能增加饱腹感的物质被用于给节食者开处方或销售,而这些物质并不能减缓他们每天的能量摄入速度,从而使他们的体重问题恶化,甚至可能增加肥胖的流行率。暗示药物或食物通过提供额外的饱腹感来帮助控制体重是错误的,原因有二。首先,激素类似物或食物成分具有可规定的饱腹感的概念在科学上是不一致的。其次,一种减肥的饱腹感是一种特殊的进食和饮水模式,其中物质没有固定的作用。必须证明这种饮食方式在使用药物或食品产品时比不使用时能使体重更大幅度地下降。在通常的进食时间抑制食物摄入并不意味着在服用药物或食用该食物期间,进食者在一个日历周期内的总能量摄入减少,从而体重下降。保持减肥和防止体重反弹的是行为模式,而不是增加饱腹感的物质。监管机构不应该允许对能量平衡基础科学的误解被利用,从而推广一种被消费者认为是避免不健康肥胖的“饱腹感”的食物或药物。