Department of Rheumatology, Manisa Hospital, Manisa Devlet Hastanesi, Manisa, Turkey.
Mod Rheumatol. 2011 Feb;21(1):89-91. doi: 10.1007/s10165-010-0345-z. Epub 2010 Aug 25.
Autoimmune disorders encompass a wide spectrum of diseases that progress with several clinical findings. They can be organ-specific (such as Hashimoto's thyroiditis) or they can involve multiple organs (such as SLE). The common characteristic of all these disorders is the production of different autoantibodies against various autoantigens along with inflammation. IgA nephropathy is the most common non-lupus glomerulopathy. It rarely coexists with SLE and has never been reported to coexist with Hashimoto's thyroiditis. In this case report, a female patient diagnosed with SLE and Hashimoto's thyroiditis and whose renal biopsy revealed IgA nephropathy is presented.
自身免疫性疾病包括一系列具有多种临床特征的疾病。它们可以是器官特异性的(如桥本甲状腺炎),也可以是多器官受累的(如系统性红斑狼疮)。所有这些疾病的共同特征是产生针对各种自身抗原的不同自身抗体以及炎症。IgA 肾病是最常见的非狼疮性肾小球病。它很少与系统性红斑狼疮共存,也从未有过与桥本甲状腺炎共存的报道。本病例报告介绍了一位女性患者,该患者被诊断为系统性红斑狼疮和桥本甲状腺炎,其肾活检显示为 IgA 肾病。