• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Relation of mucous membrane alterations to oral intake during the first year after treatment for head and neck cancer.头颈部癌症治疗后 1 年内口腔摄入与黏膜改变的关系。
Head Neck. 2011 Jun;33(6):774-9. doi: 10.1002/hed.21542. Epub 2010 Aug 24.
2
Swallowing function following postchemoradiotherapy neck dissection: review of findings and analysis of contributing factors.放化疗后颈清扫术后吞咽功能：研究结果回顾及影响因素分析。
Otolaryngol Head Neck Surg. 2011 Sep;145(3):428-34. doi: 10.1177/0194599811403075.
3
Characteristics associated with swallowing changes after concurrent chemotherapy and radiotherapy in patients with head and neck cancer.头颈部癌患者同步放化疗后吞咽变化相关特征。
Arch Otolaryngol Head Neck Surg. 2008 Oct;134(10):1060-5. doi: 10.1001/archotol.134.10.1060.
4
Dysphagia after sequential chemoradiation therapy for advanced head and neck cancer.晚期头颈癌序贯放化疗后的吞咽困难
Otolaryngol Head Neck Surg. 2006 Jun;134(6):916-22. doi: 10.1016/j.otohns.2006.02.001.
5
Dysphagia and Oral Morbidities in Chemoradiation-Treated Head and Neck Cancer Patients.接受放化疗的头颈癌患者的吞咽困难和口腔疾病
Dysphagia. 2018 Dec;33(6):739-748. doi: 10.1007/s00455-018-9895-6. Epub 2018 Apr 4.
6
Swallowing functional outcomes and nutritional status in head and neck cancer radiotherapy: longitudinal study.头颈部癌症放疗中的吞咽功能结局和营养状况：纵向研究。
BMJ Support Palliat Care. 2020 Dec;10(4):452-461. doi: 10.1136/bmjspcare-2020-002216. Epub 2020 May 13.
7
Relationship between swallow motility disorders on videofluorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy.接受放疗（无论是否联合化疗）的头颈癌患者中，吞咽造影显示的吞咽运动障碍与经口摄入量之间的关系。
Head Neck. 2006 Dec;28(12):1069-76. doi: 10.1002/hed.20459.
8
Relationship between oral intake, patient perceived swallowing impairment, and objective videofluoroscopic measures of swallowing in patients with head and neck cancer.头颈部癌症患者的口腔摄入、患者感知的吞咽障碍与客观吞咽荧光透视测量之间的关系。
Head Neck. 2019 Apr;41(4):1016-1023. doi: 10.1002/hed.25542. Epub 2018 Dec 14.
9
Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.头颈部肉瘤术后或根治性放疗后可实现良好的局部控制和生存。
Radiat Oncol. 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x.
10
[Oral mucositis as the most common complication of childhood cancer therapy. Review of the literature].[口腔黏膜炎作为儿童癌症治疗最常见的并发症。文献综述]
Orv Hetil. 2018 Apr;159(13):495-502. doi: 10.1556/650.2018.31011.

引用本文的文献

1
Effect of nutrition impact symptoms on oral nutritional supplements energy intake and use days in patients with head and neck cancer: A cross-sectional study.营养影响症状对头颈部癌症患者口服营养补充剂能量摄入和使用天数的影响：一项横断面研究。
Cancer Med. 2024 May;13(10):e7288. doi: 10.1002/cam4.7288.
2
Medial retropharyngeal nodal region sparing radiotherapy versus standard radiotherapy in patients with nasopharyngeal carcinoma: open label, non-inferiority, multicentre, randomised, phase 3 trial.中咽后淋巴结区放疗保护与鼻咽癌标准放疗比较：开放标签、非劣效性、多中心、随机、3 期临床试验。
BMJ. 2023 Feb 6;380:e072133. doi: 10.1136/bmj-2022-072133.
3
Evaluation of Mucosamin Effect on Treating Radiation Induced Oral Mucositis during and after Radiotherapy amongst Patients with Oral Cavity Squamous Cell Carcinoma.评价口腔粘膜炎防治剂（Mucosamin）在口腔鳞癌放疗中及放疗后对放射性口腔黏膜炎的防治效果。
Asian Pac J Cancer Prev. 2021 Nov 1;22(11):3711-3715. doi: 10.31557/APJCP.2021.22.11.3711.
4
Exploring the Interplay Between Radiotherapy Dose and Physiological Changes in the Swallowing Mechanism in Patients Undergoing (Chemo)radiotherapy for Oropharynx Cancer.探讨头颈部癌患者接受（放）化疗过程中放射剂量与吞咽机制生理变化之间的相互作用。
Dysphagia. 2022 Jun;37(3):567-577. doi: 10.1007/s00455-021-10307-2. Epub 2021 May 8.
5
Content analysis of rehabilitation goals for patients following non-surgical head and neck cancer treatment.非手术治疗头颈部癌症患者的康复目标的内容分析。
Support Care Cancer. 2019 Feb;27(2):639-647. doi: 10.1007/s00520-018-4364-1. Epub 2018 Jul 26.
6
Dysphagia and Oral Morbidities in Chemoradiation-Treated Head and Neck Cancer Patients.接受放化疗的头颈癌患者的吞咽困难和口腔疾病
Dysphagia. 2018 Dec;33(6):739-748. doi: 10.1007/s00455-018-9895-6. Epub 2018 Apr 4.
7
Nutrition impact symptoms and associated outcomes in post-chemoradiotherapy head and neck cancer survivors: a systematic review.放化疗后头颈部癌症幸存者的营养影响症状及相关结局：系统评价。
J Cancer Surviv. 2018 Aug;12(4):479-494. doi: 10.1007/s11764-018-0687-7. Epub 2018 Mar 20.
8
Treatment toxicities and their impact on oral intake following non-surgical management for head and neck cancer: a 3-year longitudinal study.头颈部癌症非手术治疗后的治疗毒性及其对口服摄入的影响：一项 3 年纵向研究。
Support Care Cancer. 2018 Jul;26(7):2341-2351. doi: 10.1007/s00520-018-4076-6. Epub 2018 Feb 7.
9
Chronic oral mucositis after radiotherapy to the head and neck: a new insight.头颈部放疗后慢性口腔黏膜炎：新见解
Support Care Cancer. 2016 Nov;24(11):4825-30. doi: 10.1007/s00520-016-3337-5. Epub 2016 Jul 30.
10
Pathophysiology of Radiation-Induced Dysphagia in Head and Neck Cancer.头颈部癌放疗所致吞咽困难的病理生理学
Dysphagia. 2016 Jun;31(3):339-51. doi: 10.1007/s00455-016-9710-1. Epub 2016 Apr 20.

本文引用的文献

1
Favourable impact of intensity-modulated radiation therapy on chronic dysphagia in patients with head and neck cancer.调强放射治疗对头颈癌患者慢性吞咽困难的有利影响。
Br J Radiol. 2008 Nov;81(971):865-71. doi: 10.1259/bjr/31334499.
2
Pattern analysis of acute mucosal reactions in patients with head and neck cancer treated with conventional and accelerated irradiation.头颈部癌患者接受常规和加速放疗后急性黏膜反应的模式分析
Int J Radiat Oncol Biol Phys. 2009 Feb 1;73(2):384-90. doi: 10.1016/j.ijrobp.2007.12.057. Epub 2008 Apr 18.
3
Swallowing outcomes after radiotherapy for laryngeal carcinoma.喉癌放疗后的吞咽结果。
Arch Otolaryngol Head Neck Surg. 2008 Feb;134(2):178-83. doi: 10.1001/archoto.2007.33.
4
Dysphagia after chemoradiation: analysis by modified barium swallow.放化疗后吞咽困难：改良吞钡检查分析
Ann Otol Rhinol Laryngol. 2007 Nov;116(11):837-41. doi: 10.1177/000348940711601108.
5
Reduced incidence and severity of acute radiation mucositis by WF10 (IMMUNOKINE) as adjunct to standard of cure in the management of head & neck cancer patients.在头颈部癌症患者的治疗中，WF10（免疫因子）作为标准治疗的辅助手段，可降低急性放射性粘膜炎的发生率和严重程度。
J Med Assoc Thai. 2007 Aug;90(8):1590-600.
6
Effects of treatment intensification on acute local toxicity during radiotherapy for head and neck cancer: prospective observational study validating CTCAE, version 3.0, scoring system.治疗强化对头颈部癌放疗期间急性局部毒性的影响：验证CTCAE 3.0版评分系统的前瞻性观察研究
Int J Radiat Oncol Biol Phys. 2008 Feb 1;70(2):330-7. doi: 10.1016/j.ijrobp.2007.06.022. Epub 2007 Sep 19.
7
Evaluation of some oral postradiotherapy sequelae in patients treated for head and neck tumors.头颈部肿瘤患者口腔放疗后某些后遗症的评估
Braz Oral Res. 2007 Jul-Sep;21(3):272-7. doi: 10.1590/s1806-83242007000300014.
8
A phase I study of dose-escalated chemoradiation with accelerated intensity modulated radiotherapy in locally advanced head and neck cancer.一项针对局部晚期头颈癌患者，采用剂量递增式放化疗联合加速调强放疗的I期研究。
Radiother Oncol. 2007 Oct;85(1):36-41. doi: 10.1016/j.radonc.2007.07.011. Epub 2007 Aug 20.
9
Late swallowing dysfunction and dysphagia after radiotherapy for pharynx cancer: frequency, intensity and correlation with dose and volume parameters.下咽癌放疗后的晚期吞咽功能障碍和吞咽困难：发生率、严重程度及其与剂量和体积参数的相关性
Radiother Oncol. 2007 Oct;85(1):74-82. doi: 10.1016/j.radonc.2007.06.004. Epub 2007 Jul 27.
10
High-dose cisplatin concurrent to conventionally delivered radiotherapy is associated with unacceptable toxicity in unresectable, non-metastatic stage IV head and neck squamous cell carcinoma.在不可切除的非转移性IV期头颈部鳞状细胞癌中，高剂量顺铂与传统放疗同时使用会导致不可接受的毒性。
Eur Arch Otorhinolaryngol. 2007 Dec;264(12):1475-82. doi: 10.1007/s00405-007-0395-9. Epub 2007 Jul 21.

头颈部癌症治疗后 1 年内口腔摄入与黏膜改变的关系。

Relation of mucous membrane alterations to oral intake during the first year after treatment for head and neck cancer.

机构信息

Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA.

出版信息

Head Neck. 2011 Jun;33(6):774-9. doi: 10.1002/hed.21542. Epub 2010 Aug 24.

DOI:10.1002/hed.21542
PMID:20737496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4061735/
Abstract

BACKGROUND

Acute oral mucositis is associated with pain and impaired swallowing. Little information is available on the effects of chronic mucositis on swallowing.

METHODS

Sixty patients treated for cancer of the head and neck were examined during the first year after their cancer treatment. Oral mucosa was rated with the Oral Mucositis Assessment Scale. Stimulated whole-mouth saliva, oral pain rating, percent of oral intake, and 2 subscales of the Performance Status Scale for Head and Neck (PSS-HN) cancer were also collected.

RESULTS

Mucositis scores and pain ratings decreased over time while functional measures of eating improved over time. Reduction in chronic mucositis was correlated with improved oral intake and diet.

CONCLUSION

Lack of association with pain was attributed to the absence of ulcerations. Continued impairment of oral intake during the first year posttreatment may be related to oral mucosal changes and other factors.

摘要

背景

急性口腔黏膜炎会引起疼痛和吞咽困难。关于慢性口腔黏膜炎对吞咽的影响，目前相关信息有限。

方法

在癌症治疗后的第一年，对 60 名头颈部癌症患者进行了检查。采用口腔黏膜炎评估量表评估口腔黏膜状况，同时采集唾液全口刺激量、口腔疼痛评分、口腔摄入百分比以及头颈部癌症患者生存状况评分量表（PSS-HN）的 2 个子量表。

结果

黏膜炎评分和疼痛评分随时间逐渐降低，而进食功能的衡量指标则随时间逐渐改善。慢性黏膜炎的减轻与口腔摄入和饮食的改善相关。

结论

与疼痛无关联的原因是不存在溃疡。治疗后第一年持续的口腔摄入受损可能与口腔黏膜变化和其他因素有关。