头颈部癌症治疗后 1 年内口腔摄入与黏膜改变的关系。
Relation of mucous membrane alterations to oral intake during the first year after treatment for head and neck cancer.
机构信息
Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA.
出版信息
Head Neck. 2011 Jun;33(6):774-9. doi: 10.1002/hed.21542. Epub 2010 Aug 24.
Abstract
BACKGROUND
Acute oral mucositis is associated with pain and impaired swallowing. Little information is available on the effects of chronic mucositis on swallowing.
METHODS
Sixty patients treated for cancer of the head and neck were examined during the first year after their cancer treatment. Oral mucosa was rated with the Oral Mucositis Assessment Scale. Stimulated whole-mouth saliva, oral pain rating, percent of oral intake, and 2 subscales of the Performance Status Scale for Head and Neck (PSS-HN) cancer were also collected.
RESULTS
Mucositis scores and pain ratings decreased over time while functional measures of eating improved over time. Reduction in chronic mucositis was correlated with improved oral intake and diet.
CONCLUSION
Lack of association with pain was attributed to the absence of ulcerations. Continued impairment of oral intake during the first year posttreatment may be related to oral mucosal changes and other factors.
摘要
背景
急性口腔黏膜炎会引起疼痛和吞咽困难。关于慢性口腔黏膜炎对吞咽的影响，目前相关信息有限。
方法
在癌症治疗后的第一年，对 60 名头颈部癌症患者进行了检查。采用口腔黏膜炎评估量表评估口腔黏膜状况，同时采集唾液全口刺激量、口腔疼痛评分、口腔摄入百分比以及头颈部癌症患者生存状况评分量表（PSS-HN）的 2 个子量表。
结果
黏膜炎评分和疼痛评分随时间逐渐降低，而进食功能的衡量指标则随时间逐渐改善。慢性黏膜炎的减轻与口腔摄入和饮食的改善相关。
结论
与疼痛无关联的原因是不存在溃疡。治疗后第一年持续的口腔摄入受损可能与口腔黏膜变化和其他因素有关。
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